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G. Gerna

Researcher at University of Pavia

Publications -  75
Citations -  3386

G. Gerna is an academic researcher from University of Pavia. The author has contributed to research in topics: Human cytomegalovirus & Rotavirus. The author has an hindex of 33, co-authored 75 publications receiving 3306 citations.

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Monitoring of Human Cytomegalovirus Infections and Ganciclovir Treatment in Heart Transplant Recipients by Determination of Viremia, Antigenemia, and DNAemia

TL;DR: Follow-up of HCMV infections in heart transplant recipients showed that PCR can detect viral appearance in blood 7-10 days earlier than assays for antigenemia/viremia, and viral disappearance from blood, as assessed by PCR, occurred weeks or months later than revealed by other assays.
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Comparison of different immunostaining techniques and monoclonal antibodies to the lower matrix phosphoprotein (pp65) for optimal quantitation of human cytomegalovirus antigenemia.

TL;DR: Comparison of the staining capabilities of three MAbs to pp65 with a commercially available MAb for determination of HCMV antigenemia showed that, while individual MAbs did not provide better results, the pool of MAbs detected a significantly higher number of positive peripheral blood polymorphonuclear leukocytes than Clonab CMV did.
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Monitoring of Human Cytomegalovirus‐Specific CD4+ and CD8+ T‐Cell Immunity in Patients Receiving Solid Organ Transplantation

TL;DR: The number of HCMV‐specific CD4+ and CD8+ T‐cells detected prior to transplantation significantly correlated with time to T‐cell immunity restoration, in that higher HCMv‐specific T‐ cell counts predicted earlier immune restoration.
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Isolation and characterization of two distinct human rotavirus strains with G6 specificity.

TL;DR: Two new human rotavirus strains, PA151 and PA169, with subgroup I specificity and a long RNA pattern, yet with a serotype G (VP7) specificity different from those of any of the six well-established HRV serotypes are taken into consideration when deciding strategies for the development of an effective RV vaccine.
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Comparative quantitation of human cytomegalovirus DNA in blood leukocytes and plasma of transplant and AIDS patients.

TL;DR: From a diagnostic standpoint, quantitative determination of plasmaDNAemia appears to represent a much less sensitive parameter than that of leukoDNAemia (or antigenemia) for monitoring HCMV infections and antiviral treatment.