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M. Parea

Researcher at University of Pavia

Publications -  29
Citations -  1670

M. Parea is an academic researcher from University of Pavia. The author has contributed to research in topics: Rotavirus & Human cytomegalovirus. The author has an hindex of 19, co-authored 29 publications receiving 1649 citations. Previous affiliations of M. Parea include Mario Negri Institute for Pharmacological Research.

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Monitoring of Human Cytomegalovirus Infections and Ganciclovir Treatment in Heart Transplant Recipients by Determination of Viremia, Antigenemia, and DNAemia

TL;DR: Follow-up of HCMV infections in heart transplant recipients showed that PCR can detect viral appearance in blood 7-10 days earlier than assays for antigenemia/viremia, and viral disappearance from blood, as assessed by PCR, occurred weeks or months later than revealed by other assays.
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Human Cytomegalovirus Infection of the Major Leukocyte Subpopulations and Evidence for Initial Viral Replication in Polymorphonuclear Leukocytes from Viremic Patients

TL;DR: PMNL and M/M are the subpopulations primarily involved in HCMV infection; PMNL may undergo IE replicative events and are not merely passive carriers of phagocytized viral material.
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Quantification of human cytomegalovirus viremia by using monoclonal antibodies to different viral proteins.

TL;DR: It was concluded that direct detection of HCMV IEA in PMNLs, yielding results on the day of blood collection, is a very rapid and sensitive technique, and thus one can rely on it for clinical management of H CMV infections; and low levels of viremia are clinically irrelevant, whereas high levels are associated with clinical symptoms.
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Isolation and characterization of two distinct human rotavirus strains with G6 specificity.

TL;DR: Two new human rotavirus strains, PA151 and PA169, with subgroup I specificity and a long RNA pattern, yet with a serotype G (VP7) specificity different from those of any of the six well-established HRV serotypes are taken into consideration when deciding strategies for the development of an effective RV vaccine.
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Detection of human cytomegalovirus immediate early antigen in leukocytes as a marker of viremia in immunocompromised patients.

TL;DR: Among concordant positive samples, a significant correlation was observed between the number of IEA‐positive PMN leukocytes and EA‐positive nuclei of infected fibroblasts, when the same number of PMNs were used for both tests.