G
G.M. Rukunga
Researcher at Kenya Medical Research Institute
Publications - 40
Citations - 1355
G.M. Rukunga is an academic researcher from Kenya Medical Research Institute. The author has contributed to research in topics: Plasmodium berghei & Malaria. The author has an hindex of 21, co-authored 40 publications receiving 1205 citations.
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Journal ArticleDOI
Anti-plasmodial activity and toxicity of extracts of plants used in traditional malaria therapy in Meru and Kilifi Districts of Kenya.
Peter G. Kirira,G.M. Rukunga,A. W. Wanyonyi,F.M. Muregi,J.W. Gathirwa,C.N. Muthaura,Sabah A. Omar,Festus M. Tolo,G.M. Mungai,Isaiah O. Ndiege +9 more
TL;DR: Traditional herbs used to treat malaria in Meru and Kilifi Districts, Kenya, are supported and their potential as sources of drugs for anti-malarial therapy are demonstrated.
Journal ArticleDOI
Anti-viral activity of the extracts of a Kenyan medicinal plant Carissa edulis against herpes simplex virus
Festus M. Tolo,G.M. Rukunga,Faith W. Muli,Eliud N.M. Njagi,Wilson Njue,Kazuko Kumon,G.M. Mungai,C.N. Muthaura,Joseph Muli,Lucia Keter,Esau Oishi,Mawuli W. Kofi-Tsekpo +11 more
TL;DR: Results suggest that this herbal extract has potent anti-viral agents against herpes simplex viruses that can be exploited for development of an alternative remedy for HSV infections.
Journal ArticleDOI
The in vitro anti-plasmodial and in vivo anti-malarial efficacy of combinations of some medicinal plants used traditionally for treatment of malaria by the Meru community in Kenya
J.W. Gathirwa,G.M. Rukunga,Eliud N.M. Njagi,S.A. Omar,Peter Mwitari,Anastasia N. Guantai,Festus M. Tolo,C.W. Kimani,C.N. Muthaura,Peter G. Kirira,T.N. Ndunda,G. Amalemba,G.M. Mungai,Isaiah O. Ndiege +13 more
TL;DR: A preliminary demonstration of the usefulness of combining several plants in herbal drugs, as a normal practice of traditional health practitioners, when tested in mice is demonstrated.
Journal ArticleDOI
Anti-parasitic Activity and Cytotoxicity of Selected Medicinal Plants from Kenya
Elizabeth Kigondu,G.M. Rukunga,J. M. Keriko,Willy K. Tonui,J.W. Gathirwa,Peter G. Kirira,Beatrice Irungu,Johnstone Ingonga,Isaiah O. Ndiege +8 more
TL;DR: Leishmania major infected macrophages treated with methanol extracts of Suregada zanzibariensis and Aloe nyeriensis var kedongensis and pentostam had infection rates of 28+/-2.11, 30+/-1.22 and 40+/-3.69%, respectively at 1000 microg/ml, indicating better anti-leishmanial activity for the extracts.
Journal ArticleDOI
Antimalarial activity of some plants traditionally used in treatment of malaria in Kwale district of Kenya
C.N. Muthaura,G.M. Rukunga,Sumesh C. Chhabra,Sabah A. Omar,Anastasia N. Guantai,J.W. Gathirwa,Festus M. Tolo,Peter Mwitari,Lucia Keter,Peter G. Kirira,C.W. Kimani,G.M. Mungai,Eliud N.M. Njagi +12 more
TL;DR: Results indicate that there is potential for isolation of a lead compound from the extracts of theFive medicinal plant species used for treatment of malaria in traditional/cultural health systems of Kwale people in Kenya and for their cytotoxic effects.