S
Sabah A. Omar
Researcher at Kenya Medical Research Institute
Publications - 58
Citations - 5972
Sabah A. Omar is an academic researcher from Kenya Medical Research Institute. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 30, co-authored 56 publications receiving 5444 citations. Previous affiliations of Sabah A. Omar include International Centre of Insect Physiology and Ecology.
Papers
More filters
Journal ArticleDOI
The Genetic Structure and History of Africans and African Americans
Sarah A. Tishkoff,Floyd A. Reed,Françoise R. Friedlaender,Christopher Ehret,Alessia Ranciaro,Alessia Ranciaro,Alessia Ranciaro,Alain Froment,Jibril Hirbo,Jibril Hirbo,Agnes A. Awomoyi,Jean-Marie Bodo,Ogobara K. Doumbo,Muntaser E. Ibrahim,Abdalla T. Juma,Maritha J. Kotze,Godfrey Lema,Jason H. Moore,Holly M. Mortensen,Thomas B. Nyambo,Sabah A. Omar,Kweli Powell,Gideon S. Pretorius,Michael W. Smith,Mahamadou A. Thera,Charles Wambebe,James L. Weber,Scott M. Williams +27 more
TL;DR: A detailed genetic analysis of most major groups of African populations is provided, suggesting that Africans represent 14 ancestral populations that correlate with self-described ethnicity and shared cultural and/or linguistic properties.
Journal ArticleDOI
Convergent adaptation of human lactase persistence in Africa and Europe
Sarah A. Tishkoff,Floyd A. Reed,Alessia Ranciaro,Alessia Ranciaro,Benjamin F. Voight,Courtney C. Babbitt,Jesse S. Silverman,Kweli Powell,Holly M. Mortensen,Jibril Hirbo,Maha E. Osman,Muntaser E. Ibrahim,Sabah A. Omar,Godfrey Lema,Thomas B. Nyambo,Jilur Ghori,Suzannah Bumpstead,Jonathan K. Pritchard,Gregory A. Wray,Panos Deloukas +19 more
TL;DR: A genotype-phenotype association study in Tanzanians, Kenyans and Sudanese and identified three SNPs that are associated with lactase persistence and that have derived alleles that significantly enhance transcription from the LCT promoter in vitro, providing a marked example of convergent evolution due to strong selective pressure resulting from shared cultural traits.
Journal ArticleDOI
Submicroscopic Plasmodium falciparum gametocyte densities frequently result in mosquito infection.
Petra Schneider,J. Teun Bousema,Louis Clément Gouagna,Silas Otieno,Marga van de Vegte-Bolmer,Sabah A. Omar,Robert W. Sauerwein +6 more
TL;DR: The results show that transmission occurs efficiently at sub microscopic gametocyte densities and that carriers harboring submicroscopicgametocytemia constitute a considerable proportion of the human infectious reservoir.
Journal ArticleDOI
Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs
Teun Bousema,Teun Bousema,Lucy C Okell,Lucy C Okell,Seif Shekalaghe,Jamie T. Griffin,Sabah A. Omar,Patrick Sawa,Colin J. Sutherland,Robert W. Sauerwein,Azra C. Ghani,Chris Drakeley +11 more
TL;DR: These findings confirm previous estimates of the circulation time of gametocytes, but indicate a much longer duration of (low density) gametocyte carriage after apparently successful clearance of asexual parasites.
Journal ArticleDOI
Moderate Effect of Artemisinin-Based Combination Therapy on Transmission of Plasmodium falciparum
J. Teun Bousema,Petra Schneider,Louis Clément Gouagna,Chris Drakeley,Alma Tostmann,Rein M G J Houben,John I. Githure,Rosalynn Ord,Colin J. Sutherland,Sabah A. Omar,Robert W. Sauerwein +10 more
TL;DR: The effect of ACT on malaria transmission appears to be moderate and restricted to the duration of gametocyte carriage and the proportion of mosquitoes that are infected by carriers.