G
G. Stephan
Researcher at University of California, Berkeley
Publications - 5
Citations - 265
G. Stephan is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Fluorescence in situ hybridization & Dosimetry. The author has an hindex of 5, co-authored 5 publications receiving 252 citations.
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Journal ArticleDOI
Review of translocations detected by FISH for retrospective biological dosimetry applications
Alan Edwards,Carita Lindholm,Firouz Darroudi,G. Stephan,Horst Romm,Joan Francesc Barquinero,Leonardo Barrios,M. R. Caballín,Laurence Roy,Caroline A. Whitehouse,Tawn Ej,Jayne Moquet,David Lloyd,P. Voisin +13 more
TL;DR: The technique works and a lifetime dose to the bone marrow from low-linear energy transfer radiation of 0.5 Gy above normal background levels can be measured for any individual.
Journal ArticleDOI
Translocation yields in peripheral blood lymphocytes from control populations
Caroline A. Whitehouse,Alan Edwards,Tawn Ej,G. Stephan,Ursula Oestreicher,Jayne Moquet,David Lloyd,Laurence Roy,P. Voisin,Carita Lindholm,Joan Francesc Barquinero,Leonardo Barrios,M. R. Caballín,Firouz Darroudi,Fomina J +14 more
TL;DR: There is a strong variation of translocation yield with age but no variation was detectable with gender or smoking habits, and a generic age-dependent control level can be assumed for retrospective biological dosimetry purposes.
Journal ArticleDOI
Intercomparison of translocation and dicentric frequencies between laboratories in a follow-up of the radiological accident in Estonia.
TL;DR: The results imply that relatively consistent scoring data were obtained with different chromosome painting protocols and support the idea that the reduction of translocations with time is associated with partial-body irradiation.
Journal ArticleDOI
Effect of americium‐241 α‐particles on the dose–response of chromosome aberrations in human lymphocytes analysed by fluorescence in situ hybridization
TL;DR: FISH‐based analysis of complex rearrangements allows discrimination between partial‐body exposures to low‐linear energy transfer radiation and high‐ linear energy transfer exposures, and in assessing past or chronic exposure to α‐particles, the use of a dose–effect curve obtained by FISH‐ based translocation data, which had not excluded data determined in unstable cells, would underestimate the dose.
Journal ArticleDOI
Analysis of α‐particle induced chromosome aberrations in human lymphocytes, using pan‐centromeric and pan‐telomeric probes
Marta Mestres,M. R. Caballín,E. Schmid,G. Stephan,R. Sachs,Lleonard Barrios,Joan Francesc Barquinero +6 more
TL;DR: The results seem to indicate that compared to low‐LET radiation, after α‐particle exposure centromere‐containing elements are more likely to be repaired.