G
G. Stephanou
Researcher at University of Patras
Publications - 37
Citations - 788
G. Stephanou is an academic researcher from University of Patras. The author has contributed to research in topics: Micronucleus test & Chromosome breakage. The author has an hindex of 16, co-authored 37 publications receiving 761 citations.
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Journal ArticleDOI
Chromosomal aberrations, sister-chromatid exchanges, cells with high frequency of SCE, micronuclei and comet assay parameters in 1,3-butadiene-exposed workers
Radim J. Sram,Pavel Rossner,Kimmo Peltonen,K. Podrazilová,Gabriela Mračková,N.A. Demopoulos,G. Stephanou,D. Vlachodimitropoulos,Firouz Darroudi,Ad D. Tates +9 more
TL;DR: BD exposure had no significant effects on formation of micronuclei and on comet assay parameters, and effect of smoking was observed only for HFC in BD-exposed group.
Journal ArticleDOI
Biological effect monitoring in industrial workers from the Czech Republic exposed to low levels of butadiene.
Ad D. Tates,F.J. van Dam,F.A. de Zwart,Firouz Darroudi,Adayapalam T. Natarajan,Pavel Rossner,K. Peterková,Kimmo Peltonen,N.A. Demopoulos,G. Stephanou,D. Vlachodimitropoulos,Radim J. Sram +11 more
TL;DR: Blood samples were collected twice from 19 workers exposed to 1,3-butadiene and 19 matched controls and analysis of chromosomal aberrations in lymphocytes from 1994 subjects indicated that the percentage of aberrant cells was significantly enhanced in exposed subjects.
Journal ArticleDOI
Human cytogenetic biomonitoring of occupational exposure to 1,3-butadiene
Marja Sorsa,K. Autio,N.A. Demopoulos,H. Järventaus,Pavel Rossner,Radim J. Sram,G. Stephanou,D. Vlachodimitropoulos +7 more
TL;DR: The association of occupational exposure to 1,3-butadiene and chromosomal damage in peripheral blood lymphocytes was studied in 40 workers from two production facilities, representing typical low exposure levels of the butadiene manufacturing industry.
Journal ArticleDOI
Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke
Panagiotis Georgiadis,N.A. Demopoulos,Jan Topinka,G. Stephanou,M. Stoikidou,M. Bekyrou,K. Katsouyianni,Radim J. Sram,Herman Autrup,Soterios A. Kyrtopoulos +9 more
TL;DR: A significant trend of increasing DNA adduct levels only among individuals with at least one CYP1A1*2A mutated allele is observed, illustrating the importance and complexity of gene-exposure and gene-gene interactions in determining the level of genotoxic damage on an individual levels.
Journal ArticleDOI
Interactions between CYP1A1 polymorphisms and exposure to environmental tobacco smoke in the modulation of lymphocyte bulky DNA adducts and chromosomal aberrations.
Panagiotis Georgiadis,Jan Topinka,Dimitris Vlachodimitropoulos,M. Stoikidou,Maria Gioka,G. Stephanou,Herman Autrup,Nikolaos A. Demopoulos,Klea Katsouyanni,Radim J. Sram,Soterios A. Kyrtopoulos +10 more
TL;DR: The levels of both biomarkers responded in a parallel fashion to changes in exposure/CYP1A1*2A genotype combinations during both seasons and suggest that subjects with these genotypes may have increased susceptibility to the genotoxic effects of ETS.