G
Gabriel E. Pantelias
Publications - 5
Citations - 153
Gabriel E. Pantelias is an academic researcher. The author has contributed to research in topics: Fusion gene & ABL. The author has an hindex of 5, co-authored 5 publications receiving 105 citations.
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The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer
Theodoros Rampias,Dimitris Karagiannis,Margaritis Avgeris,Alexander Polyzos,Antonis Kokkalis,Zoi Kanaki,Evgenia Kousidou,Maria Tzetis,E. Kanavakis,Konstantinos Stravodimos,Kalliopi N. Manola,Gabriel E. Pantelias,Andreas Scorilas,Apostolos Klinakis +13 more
TL;DR: It is shown that downregulation of K MT2C in bladder cancer cells leads to extensive changes in the epigenetic status and the expression of DNA damage response and DNA repair genes, suggesting that cancer cells with low KMT2C expression are attractive targets for therapies with PARP1/2 inhibitors.
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Cytogenetic abnormalities and monosomal karyotypes in children and adolescents with acute myeloid leukemia: correlations with clinical characteristics and outcome
Kalliopi N. Manola,Fotios Panitsas,Sophia Polychronopoulou,Aggeliki Daraki,Maria Karakosta,Cryssa Stavropoulou,Georgia Avgerinou,Emmanuel Hatzipantelis,Gabriel E. Pantelias,Constantina Sambani,Maria Pagoni +10 more
TL;DR: Patients with the t(15;17) had the most favorable outcomes, whereas patients with 11q23 rearrangements and monosomy 7 had the worst outcomes.
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Jumping translocations in hematological malignancies: a cytogenetic study of five cases
Kalliopi N. Manola,Vasileios N. Georgakakos,Chryssa Stavropoulou,Alexandros Spyridonidis,Maria K. Angelopoulou,Ioanna Vlachadami,Andreas Katsigiannis,Paraskevi Roussou,Gabriel E. Pantelias,Constantina Sambani +9 more
TL;DR: The investigation suggests that JT may not contribute to the pathogenesis but rather to the progression of the disease, and it demonstrates that chromosome band 1q10 as a breakpoint of the donor chromosome 1q is also implicated in AML, not only in multiple myeloma as it has been known until now.
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Association of A(313)G glutathione S-transferase P1 germline polymorphism with susceptibility to de novo myelodysplastic syndrome.
Sophia Zachaki,Chrysa Stavropoulou,Marina Kalomoiraki,Theodora Koromila,Aggeliki Daraki,Kalliopi N. Manola,Ariadni Mavrou,Emmanuel Kanavakis,Gabriel E. Pantelias,Constantina Sambani +9 more
TL;DR: The results provide evidence for a pathogenetic role of the GSTP1 polymorphism in MDS risk, probably in an age-dependent manner.
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Disruption of the ETV6 gene as a consequence of a rare translocation (12;12)(p13;q13) in treatment-induced acute myeloid leukemia after breast cancer
Kalliopi N. Manola,Vasileios N. Georgakakos,Dimitris Margaritis,Chryssa Stavropoulou,Christos Panos,Ioannis Kotsianidis,Gabriel E. Pantelias,Constantina Sambani +7 more
TL;DR: To the best of the knowledge, this patient represents the first report of the rare t(12;12)(p13;q13) described in treatment-induced leukemia and the possible formation of a new fusion gene.