K
Konstantinos Stravodimos
Researcher at National and Kapodistrian University of Athens
Publications - 118
Citations - 2680
Konstantinos Stravodimos is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Bladder cancer & Medicine. The author has an hindex of 27, co-authored 103 publications receiving 2303 citations. Previous affiliations of Konstantinos Stravodimos include Albert Einstein College of Medicine & Athens State University.
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Journal ArticleDOI
Differences in ureteroscopic stone treatment and outcomes for distal, mid-, proximal, or multiple ureteral locations: the Clinical Research Office of the Endourological Society ureteroscopy global study.
Enrique Perez Castro,Palle Jørn Sloth Osther,V. Jinga,Hassan Razvi,Konstantinos Stravodimos,Kandarp Parikh,Ali Riza Kural,Jean J.M.C.H. de la Rosette +7 more
TL;DR: This study shows that patients who have ureteral stones can be treated successfully with Ureteroscopy with a low rate of complications for the patient, and good stone-free rates with low morbidity.
Journal ArticleDOI
A new tumor suppressor role for the Notch pathway in bladder cancer
Theodoros Rampias,Paraskevi Vgenopoulou,Margaritis Avgeris,Alexander Polyzos,Konstantinos Stravodimos,Christos Valavanis,Andreas Scorilas,Apostolos Klinakis +7 more
TL;DR: It is shown that Notch activation in bladder cancer cells suppresses proliferation both in vitro and in vivo by directly upregulating dual-specificity phosphatases (DUSPs), thus reducing the phosphorylation of ERK1 and ERK2 (ERK1/2).
Journal ArticleDOI
Profilin 1 is a Potential Biomarker for Bladder Cancer Aggressiveness
Jerome Zoidakis,Manousos Makridakis,Panagiotis Zerefos,Vasiliki Bitsika,Sergio Esteban,Maria Frantzi,Konstantinos Stravodimos,Nikolaos P. Anagnou,Nikolaos P. Anagnou,Maria G. Roubelakis,Marta Sanchez-Carbayo,Antonia Vlahou +11 more
TL;DR: This study involves the application of a fractionation method of urinary proteins based on the use of immobilized metal affinity chromatography for the discovery of biomarkers for aggressive BC and reveals the association of profilin 1 with BC paving the way for its further investigation in BC stratification.
Journal ArticleDOI
Prediction of muscle-invasive bladder cancer using urinary proteomics.
Eric Schiffer,Antonia Vlahou,Andreas Petrolekas,Konstantinos Stravodimos,Robert Tauber,Jürgen E. Geschwend,Jochen Neuhaus,Jens-Uwe Stolzenburg,Mark R. Conaway,Harald Mischak,Dan Theodorescu +10 more
TL;DR: Use of urinary peptides seems promising in estimating the probability a patient harbors muscle-invasive urothelial bladder cancer, and may also shed novel insights into the biology of bladder tumor progression not obtainable by other methods.
Journal ArticleDOI
Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis
Agnieszka Latosinska,Agnieszka Latosinska,Konstantinos Vougas,Manousos Makridakis,Julie Klein,Julie Klein,William Mullen,Mahmoud Abbas,Konstantinos Stravodimos,Ioannis Katafigiotis,Axel S. Merseburger,Jerome Zoidakis,Harald Mischak,Antonia Vlahou,Vera Jankowski +14 more
TL;DR: Conclusively, both label-free and iTRAQ (when combined to peptide fractionation) provide high proteome coverage and apparently valid predictions in terms of differential expression, neverthelesslabel-free provides higher sequence coverage and ultimately detects a higher number of differentially expressed proteins.