G
Gabriele Carullo
Researcher at University of Siena
Publications - 61
Citations - 1099
Gabriele Carullo is an academic researcher from University of Siena. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 14, co-authored 47 publications receiving 590 citations. Previous affiliations of Gabriele Carullo include University of Calabria.
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Journal ArticleDOI
Quercetin and derivatives: useful tools in inflammation and pain management
Gabriele Carullo,Anna Rita Cappello,Luca Frattaruolo,Mariateresa Badolato,Biagio Armentano,Francesca Aiello +5 more
TL;DR: The analgesic property of quercetin, intrinsically linked to its anti-inflammatory action, has been evaluated, to investigate about an innovative approach to this interesting natural compound, such as analgesic remedial.
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Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway
Luca Frattaruolo,Gabriele Carullo,Matteo Brindisi,Sarah Mazzotta,Sarah Mazzotta,Luca Bellissimo,Vittoria Rago,Rosita Curcio,Vincenza Dolce,Francesca Aiello,Anna Rita Cappello +10 more
TL;DR: Interestingly, licoflavanone markedly decreased pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels, highlighting the potential of this natural compound as a new scaffold in anti-inflammatory drug research.
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From the hive: Honey, a novel weapon against cancer.
TL;DR: Scientific results highlight that honey and its active compounds could be used as immune booster for patients undergoing chemotherapy, and showed protective effects against the common exasperating and disabling side effects, mostly mucositis.
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Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.
Stefano Federico,Luca Pozzetti,Alessandro Papa,Gabriele Carullo,Sandra Gemma,Stefania Butini,Giuseppe Campiani,Nicola Relitti +7 more
TL;DR: This perspective will highlight the recent discoveries in this field emphasizing the role of TLR isoforms in different diseases, the therapeutic effect of their natural and synthetic modulators and will discuss insights for the future exploitation of TLRs modulators in human health.
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Structure–activity relationships for the synthesis of selective cyclooxygenase 2 inhibitors: an overview (2009–2016)
TL;DR: This manuscript highlights the structure-activity relationships which characterize the chemical scaffolds endowed with selective COX-2 inhibition and the role of COx-2 inhibitors in the pain phenomenon and cancer is discussed.