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Sarah Mazzotta
Researcher at University of Calabria
Publications - 25
Citations - 258
Sarah Mazzotta is an academic researcher from University of Calabria. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 5, co-authored 17 publications receiving 108 citations. Previous affiliations of Sarah Mazzotta include University of Milan & University of Seville.
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Journal ArticleDOI
Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway
Luca Frattaruolo,Gabriele Carullo,Matteo Brindisi,Sarah Mazzotta,Sarah Mazzotta,Luca Bellissimo,Vittoria Rago,Rosita Curcio,Vincenza Dolce,Francesca Aiello,Anna Rita Cappello +10 more
TL;DR: Interestingly, licoflavanone markedly decreased pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels, highlighting the potential of this natural compound as a new scaffold in anti-inflammatory drug research.
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Analytical profile and antioxidant and anti-inflammatory activities of the enriched polyphenol fractions isolated from bergamot fruit and leave
Giovanna Baron,Alessandra Altomare,Marco Mol,Jéssica Leite Garcia,Jéssica Leite Garcia,Camila Renata Corrêa,Angela Raucci,Luigi Mancinelli,Sarah Mazzotta,Laura Fumagalli,Giuseppe Trunfio,Luigi Tucci,Elena Lombardo,Domenico Malara,Elzbieta Janda,Vincenzo Mollace,Marina Carini,Ezio Bombardelli,Giancarlo Aldini +18 more
TL;DR: In this article, the authors compared the qualitative and semi-quantitative profiles of the polyphenol fraction purified from the leaf (BLPF) and fruit (BFPF) of bergamot (Citrus bergamia), and evaluated their antioxidant and anti-inflammatory activity.
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Pinocembrin and its linolenoyl ester derivative induce wound healing activity in HaCaT cell line potentially involving a GPR120/FFA4 mediated pathway
Sarah Mazzotta,Paolo Governa,Vittoria Borgonetti,Paola Marcolongo,Claudio Nanni,Alessandra Gamberucci,Fabrizio Manetti,Federica Pessina,Gabriele Carullo,Antonella Brizzi,Francesca Aiello +10 more
TL;DR: In this paper, Pinocembrin (HW0) was evaluated as a suitable compound for interacting with GPR120, and was hybridized with fatty acids to enhance the wound healing potential and GPR-120 interactions.
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3-Amino-alkylated indoles: Unexplored green products acting as anti-inflammatory agents
Sarah Mazzotta,Sarah Mazzotta,Luca Frattaruolo,Matteo Brindisi,Cristina Ulivieri,Francesca Vanni,Antonella Brizzi,Gabriele Carullo,Anna Rita Cappello,Francesca Aiello +9 more
TL;DR: The outcomes highlight the importance of the indole substitution in the anti-inflammatory activity of these compounds, exerted by acting on the interlinked NF-κB/ERK1/2 pathways.
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GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery.
Gabriele Carullo,Sarah Mazzotta,Margarita Vega-Holm,Fernando Iglesias-Guerra,José M. Vega-Pérez,Francesca Aiello,Antonella Brizzi +6 more
TL;DR: In this paper, the authors highlight the importance of GPR120 in Type 2 diabetes mellitus (T2DM) and highlight the starting point for the future discovery of GPCR120 agonists as antidiabetic drugs.