Galo L. Mejia

TL;DR: It is shown that the TMEM97 gene is expressed in mouse and human dorsal root ganglion including populations of neurons that are involved in pain; however, the gene is also likely expressed in non-neuronal cells that may contribute to the observed behavioral effects.

TL;DR: It is shown that an Mtb organic extract activates nociceptive neurons in vitro and the Mtb glycolipid sulfolipid-1 (SL-1) as the nocICEptive molecule and Mtb-infected guinea pigs cough in a manner dependent on SL-1 synthesis.

TL;DR: A novel role for descending dopaminergic neurons in the maintenance of pathological pain plasticity is demonstrated, consistent with reconsolidation-like effects in the spinal dorsal horn.

TL;DR: A neuropathic pain model in mice is used to demonstrate that male (but not female) mice show a robust pain-related deficit in attentional set-shifting, which is associated with structural plasticity in axon initial segments in the infralimbic cortex.

TL;DR: This work is consistent with previous findings that P2XR and p38 inhibition can lead to male-specific effects on pain behaviors in mice, however, given that microglial activation at time points where these drugs were effective, it is questioned whether these effects can be completely attributed to microglia.