G
Gang Jian Qin
Researcher at Northwestern University
Publications - 1
Citations - 41
Gang Jian Qin is an academic researcher from Northwestern University. The author has contributed to research in topics: Apoptosis & Trichostatin A. The author has an hindex of 1, co-authored 1 publications receiving 31 citations.
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HDAC4 degradation mediates HDAC inhibition-induced protective effects against hypoxia/reoxygenation injury.
TL;DR: It is demonstrated that HDAC inhibition stimulates proteasome dependent degradation of HDAC4, which is associated withHDAC4 sumoylation to induce these protective effects, and TSA treatment resulted in a decrease in HDAC 4 in cardiomyocytes infected with adenoviral HDac4, and HDAC3‐induced injury was attenuated by TSA.