G
Gary Brodsky
Researcher at University of Colorado Denver
Publications - 18
Citations - 1070
Gary Brodsky is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Platelet & Gene mutation. The author has an hindex of 11, co-authored 18 publications receiving 988 citations. Previous affiliations of Gary Brodsky include University of Colorado Boulder & Anschutz Medical Campus.
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Journal ArticleDOI
Natural history of dilated cardiomyopathy due to lamin A/C gene mutations.
Matthew R.G. Taylor,Pamela R. Fain,Pamela R. Fain,Gianfranco Sinagra,Misi L. Robinson,Alastair D. Robertson,Elisa Carniel,Andrea Di Lenarda,Teresa J. Bohlmeyer,Debra A. Ferguson,Gary Brodsky,Mark M. Boucek,Mark M. Boucek,Jean Lascor,Andrew C Moss,Wai Lun P Li,Wai Lun P Li,Gary L. Stetler,Francesco Muntoni,Michael R. Bristow,Luisa Mestroni +20 more
TL;DR: Mutation screening should be considered in patients with DCM, in particular when clinical predictors of LMNA mutation are present, regardless of family history.
Journal ArticleDOI
Lamin A/C gene mutation associated with dilated cardiomyopathy with variable skeletal muscle involvement.
Gary Brodsky,Francesco Muntoni,Snjezana Miocic,Gianfranco Sinagra,Caroline Sewry,Luisa Mestroni +5 more
TL;DR: The lamin A/C gene was examined in the MDDC1 family and a single nucleotide deletion was identified within exon 6, and all affected individuals were found to be heterozygous for this deletion.
Journal ArticleDOI
Sources of variability in platelet accumulation on type 1 fibrillar collagen in microfluidic flow assays.
Keith B. Neeves,Keith B. Neeves,Abimbola A. Onasoga,Ryan R. Hansen,Jessica J. Lilly,Diana Venckunaite,Meghan B. Sumner,Andrew Irish,Gary Brodsky,Marilyn J. Manco-Johnson,Jorge Di Paola +10 more
TL;DR: This study is the largest association study of MFA in healthy donors and will likely set up the basis for the determination of the normal range of platelet responses in this type of assay.
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A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment.
Kenneth N. Maclean,Jakub Sikora,Viktor Kožich,Hua Jiang,Lori S. Greiner,Eva Kraus,Jakub Krijt,Katherine H. Overdier,Renata Collard,Gary Brodsky,Lynne Meltesen,Linda S. Crnic,Robert H. Allen,Sally P. Stabler,Milan Elleder,Rima Rozen,David Patterson,Jan P. Kraus +17 more
TL;DR: Tail bleeding determinations indicate that HO mice are in a hypercoagulative state that is significantly ameliorated by betaine treatment in a manner that recapitulates the disease as it occurs in humans.
Journal ArticleDOI
Hypoplastic left heart syndrome myocytes are differentiated but possess a unique phenotype.
Teresa J. Bohlmeyer,Steve M. Helmke,Shuping Ge,Jennifer Lynch,Gary Brodsky,James H Sederberg,Alastair D. Robertson,Wayne Minobe,Michael R. Bristow,M. Benjamin Perryman +9 more
TL;DR: Findings indicate that myocytes from HLHS syndrome patients, while differentiated, have a unique gene expression pattern.