G
Gary Tanigawa
Researcher at Howard Hughes Medical Institute
Publications - 4
Citations - 1528
Gary Tanigawa is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Transgene & Beta (finance). The author has an hindex of 3, co-authored 4 publications receiving 1448 citations.
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Journal ArticleDOI
A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation
Anja A.T. Geisterfer-Lowrance,Susan Kass,Gary Tanigawa,Hans-Peter Vosberg,William J. McKenna,Christine E. Seidman,Jon G. Seidman +6 more
TL;DR: Identification of two unique mutations within cardiac MHC genes in all individuals with FHC from two unrelated families demonstrates that defects in the cardiac M HC genes can cause this disease.
Journal ArticleDOI
A molecular basis for familial hypertrophic cardiomyopathy: An αβ cardiac myosin heavy chain hybrid gene
Gary Tanigawa,John A. Jarcho,Susan Kass,Scott D. Solomon,Hans-Peter Vosberg,Jon G. Seidman,Christine E. Seidman,Christine E. Seidman +7 more
TL;DR: It is demonstrated here and in the accompanying article that the cardiac MHC genes, which encode integral myofibrillar components, are mutated in all affected individuals from two unrelated familles with FHC.
Journal ArticleDOI
Progression to diabetes in nonobese diabetic (NOD) mice with transgenic T cell receptors
Myra A. Lipes,Anthony Rosenzweig,Anthony Rosenzweig,Kut-Nie Tan,Gary Tanigawa,Dan Ladd,Jonathan G. Seidman,George S. Eisenbarth +7 more
TL;DR: The T cell receptor (TCR) requirements in the pathogenesis of insulin-dependent diabetes were examined with transgenic NOD animals bearing nondisease-related TCR alpha and beta chains and skewing the TCR repertoire did not diminish autoimmune susceptibility in NOD mice.