G
Geetha Ramakrishnan
Researcher at University of Alberta
Publications - 4
Citations - 306
Geetha Ramakrishnan is an academic researcher from University of Alberta. The author has contributed to research in topics: Acyltransferase & Lysophosphatidic acid. The author has an hindex of 4, co-authored 4 publications receiving 281 citations. Previous affiliations of Geetha Ramakrishnan include University of California, San Diego & Indian Institute of Science.
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CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid
TL;DR: It is reported that human CGI-58 is closely related to ICT1 and the role of cgi-58 as an acyltransferase is revealed, suggesting the existence of an alternate cytosolic phosphatidic acid biosynthetic pathway in the white adipose tissue.
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Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy
Taras Y. Nazarko,Katharine Ozeki,Andreas Till,Geetha Ramakrishnan,Pouya Lotfi,Mingda Yan,Suresh Subramani +6 more
TL;DR: The acyl-CoA–binding protein Atg37 is a new component of the pexophagic receptor protein complex that regulates the recruitment of Atg11 by Atg30 in the peroxisomal membrane during pexphagy.
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YLR099C (ICT1) Encodes a Soluble Acyl-CoA-dependent Lysophosphatidic Acid Acyltransferase Responsible for Enhanced Phospholipid Synthesis on Organic Solvent Stress in Saccharomyces cerevisiae
TL;DR: This study provides a mechanism for organic solvent tolerance from the point of membrane dynamics in S. cerevisiae by reporting for the first time that an increase in the synthesis of phosphatidic acid is responsible for enhanced phospholipid synthesis that confers tolerance to the organic solvent in Saccharomyces Cerevisiae.
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Multiple mechanisms contribute to increased neutral lipid accumulation in yeast producing recombinant variants of plant diacylglycerol acyltransferase 1.
Yang Xu,Guanqun Chen,Michael S. Greer,Kristian Mark P. Caldo,Geetha Ramakrishnan,Saleh Shah,Limin Wu,M. Joanne Lemieux,Jocelyn A. Ozga,Randall J. Weselake +9 more
TL;DR: The amino acid residue substitutions that conferred increased TAG accumulation were shown to be present in the DGAT1-PTMD9 region of other higher plant species and has potentially broad applications in genetic engineering of oleaginous crops and microorganisms.