G
Geltrude Mingrone
Researcher at King's College London
Publications - 454
Citations - 24376
Geltrude Mingrone is an academic researcher from King's College London. The author has contributed to research in topics: Insulin resistance & Insulin. The author has an hindex of 61, co-authored 426 publications receiving 19664 citations. Previous affiliations of Geltrude Mingrone include The Catholic University of America & University of Ferrara.
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Journal ArticleDOI
Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris
Juan Francisco Miquel,C. Covarrubias,Luis Villaroel,Geltrude Mingrone,Aldo V. Greco,L Puglielli,Pilar Carvallo,Guillermo Marshall,Guido del Pino,Flavio Nervi +9 more
TL;DR: Cholesterol lithogenic genes appear widely spread among Chilean Indians and Hispanics and could determine the early formation of gallstones and explain the high prevalence of gallbladder diseases among some South American populations.
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Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial.
Geltrude Mingrone,Geltrude Mingrone,Geltrude Mingrone,Simona Panunzi,Andrea De Gaetano,Caterina Guidone,Caterina Guidone,Amerigo Iaconelli,Amerigo Iaconelli,Esmeralda Capristo,Esmeralda Capristo,Ghassan Chamseddine,Stefan R. Bornstein,Francesco Rubino,Francesco Rubino +14 more
TL;DR: A 10-year follow-up study of an open-label, single-centre (tertiary hospital in Rome, Italy), randomised controlled trial, in which patients with type 2 diabetes (baseline duration >5 years; glycated haemoglobin [HbA1c] >7·0, and body-mass index ≥35 kg/m2) were randomly assigned to medical therapy, Roux-en-Y gastric bypass (RYGB), or biliopancreatic diversion (BPD) by a computerised system RE
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Gut microbiome-derived metabolites characterize a peculiar obese urinary metabotype
Riccardo Calvani,Alfredo Miccheli,Giorgio Capuani,A Tomassini Miccheli,Caterina Puccetti,Maurizio Delfini,Amerigo Iaconelli,Giuseppe Nanni,Geltrude Mingrone +8 more
TL;DR: Preliminary results confirmed that in humans the gut microflora metabolism is strongly linked to the obesity phenotype, and the typical obese metabotype is lost after weight loss induced by bariatric surgery.
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Influence of maternal obesity on insulin sensitivity and secretion in offspring.
Geltrude Mingrone,Melania Manco,Maria Elena Valera Mora,Caterina Guidone,Amerigo Iaconelli,Donatella Gniuli,Laura Leccesi,Chiara Chiellini,Giovanni Ghirlanda +8 more
TL;DR: The maternal genetic/epigenetic transmission shows a clear sexual dimorphism, with male offspring having a higher value of insulin sensitivity (although not statistically significant) associated with significantly higher insulin secretion than female offspring.
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Effects of dietary fatty acids on insulin sensitivity and secretion.
TL;DR: The biochemical mechanisms responsible for lower fatty acid oxidation involve reduced carnitine palmitoyl transferase activity, as a likely consequence of increased intracellular concentrations of malonyl‐CoA; reduced glycogen synthase activity; and impairment of insulin signalling and glucose transport.