G
Gene A. Hines
Researcher at University of Alabama at Birmingham
Publications - 24
Citations - 806
Gene A. Hines is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Dehydroepiandrosterone & Dehydroepiandrosterone sulfate. The author has an hindex of 18, co-authored 24 publications receiving 785 citations. Previous affiliations of Gene A. Hines include University of Puerto Rico & University of New Hampshire.
Papers
More filters
Journal ArticleDOI
Adrenal androgen excess in the polycystic ovary syndrome : Sensitivity and responsivity of the hypothalamic-pituitary-adrenal axis
TL;DR: It is postulated that excess AAs in PCOS arises from dysfunction of the hypothalamic-pituitary-adrenal axis, due to exaggerated pituitary secretion of ACTH in response to hypothalamic CRH, and excess sensitivity/responsivity of AAs to ACTH stimulation.
Journal ArticleDOI
Effects of aging on adrenal function in the human: responsiveness and sensitivity of adrenal androgens and cortisol to adrenocorticotropin in premenopausal and postmenopausal women.
C. Richard Parker,S.M. Slayden,Ricardo Azziz,S. Lolita Crabbe,Gene A. Hines,Larry R. Boots,Sejong Bae +6 more
TL;DR: The data demonstrate that the deficiency in adrenal androgen production in women is restricted to the delta5-pathway steroid products (DHEA and DS), whereas there is no reduction in the capacity of the adrenal to produce A4 or cortisol.
Journal ArticleDOI
Sex steroid levels in the testes, ovaries, and pyloric caeca during gametogenesis in the sea star Asterias vulgaris
TL;DR: It is hypothesized that transient increases in the levels of sex steroids during gametogenesis may serve as endogenous modulators of reproduction.
Journal ArticleDOI
Influence of insulin and testosterone on adrenocortical steroidogenesis in vitro: preliminary studies.
TL;DR: It is clear that extra-adrenal factors such as insulin and T have some adrenal regulatory capacity, and insulin stimulated DHEAS and decreased DHEA production, suggesting that it increases adrenocortical sulfotransferase activity.
Journal ArticleDOI
Levels of progesterone, testosterone, and estradiol, and androstenedione metabolism in the gonads of Lytechinus variegatus (Echinodermata:echinoidea).
TL;DR: The sex-specific pattern of accumulation of 5 alpha-adiols in the ovaries and testes suggests that the 5alpha- adiols may affect processes related to reproduction in L. variegatus.