G
Genji Imokawa
Researcher at Chubu University
Publications - 272
Citations - 12149
Genji Imokawa is an academic researcher from Chubu University. The author has contributed to research in topics: Stratum corneum & Ceramide. The author has an hindex of 58, co-authored 267 publications receiving 11595 citations. Previous affiliations of Genji Imokawa include United States Naval Research Laboratory & University of Tokyo.
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Decreased level of ceramides in stratum corneum of atopic dermatitis : an etiologic factor in atopic dry skin ?
TL;DR: Findings suggest that an insufficiency of ceramides in the stratum corneum is an etiologic factor in atopic dry skin.
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Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis.
T Kobayashi,Kazunori Urabe,A. Winder,Celia Jiménez-Cervantes,Genji Imokawa,T. Brewington,Francisco Solano,José C. García-Borrón,Vincent J. Hearing +8 more
TL;DR: The data demonstrate that the specific melanogenic function of TRP1 is the oxidation of 5,6‐dihydroxyindole‐2‐carboxylic acid (DHICA) to a carboxylated indole‐quinone at a down‐stream point in the melanin biosynthetic pathway.
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Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes
TL;DR: It is shown here that the growth factors for human melanocytes are produced and secreted by the surrounding cells, namely human keratinocytes for ET-1 and Big-ET-1, which play an essential role in the maintenance of melanocyte proliferation and UV hyperpigmentation in the epidermis.
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Age-related changes in the elastic properties and thickness of human facial skin
TL;DR: Skin thickness decreased with age in ventral forearm skin, but increased significantly in the skin of the forehead, corners of the eyes, and cheeks, which are markedly exposed to sunlight.
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Effects of endothelins on signal transduction and proliferation in human melanocytes.
TL;DR: It is demonstrated here that human melanocytes could be regulated by endothelin (ET) derivatives, potent vasoconstrictive peptides synthesized by endothelial cells, to stimulate their proliferation and melanization via a receptor-mediated signal transduction pathway.