G
George B. Richerson
Researcher at University of Iowa
Publications - 146
Citations - 10390
George B. Richerson is an academic researcher from University of Iowa. The author has contributed to research in topics: Epilepsy & Raphe. The author has an hindex of 52, co-authored 141 publications receiving 9172 citations. Previous affiliations of George B. Richerson include Case Western Reserve University & United States Department of Veterans Affairs.
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Journal ArticleDOI
Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder
Wei Du,Jocelyn F. Bautista,Jocelyn F. Bautista,Huanghe Yang,Ana Díez-Sampedro,Sun Ah You,Sun Ah You,Lejin Wang,Lejin Wang,Prakash Kotagal,Hans Lüders,Jingyi Shi,Jianmin Cui,George B. Richerson,Qing Kenneth Wang +14 more
TL;DR: It is proposed that enhancement of BK channels in vivo leads to increased excitability by inducing rapid repolarization of action potentials, resulting in generalized epilepsy and paroxysmal dyskinesia by allowing neurons to fire at a faster rate.
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Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis.
TL;DR: Serotonergic neurons in the medulla have been shown to be sensors of carbon dioxide and pH, and this role in control of pH homeostasis could provide a neurobiological explanation for the link between changes in the serotonin system and sudden infant death syndrome (SIDS).
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Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention.
TL;DR: Because generalised tonic-clonic seizures precede most cases of SUDEP, patients must be better educated about prevention and the value of nocturnal monitoring to detect seizures and postictal stimulation is unproven but warrants further study.
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Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices.
TL;DR: The size of synaptic quanta has been found to display considerable variation in cultured hippocampal neurons, but the source of this variability was previously unknown, and the properties of locally evoked miniature excitatory postsynaptic currents in cultured neurons and in thin hippocampal slices using whole-cell patch-clamp recordings are compared.
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Impaired Respiratory and Body Temperature Control Upon Acute Serotonergic Neuron Inhibition
Russell S. Ray,Andrea E. Corcoran,Rachael D. Brust,Jun Chul Kim,George B. Richerson,Eugene E. Nattie,Susan M. Dymecki +6 more
TL;DR: It is established that serotonergic neurons regulate life-sustaining respiratory and thermoregulatory networks, and a noninvasive tool for mapping neuron function is demonstrated.