George Karigiannis

TL;DR: The structure and the biological significance of naturally occurring and synthetic polyamine analogues and conjugates are presented and the available methodologies for their synthesis are described.

TL;DR: In this article, all four isomers of the spermine alkaloid kukoamine were unambiguously prepared through diacylation with O,O′ -dibenzylcaffeyl chloride of suitably protected (benzyl and/or trityl groups) spermin derivatives, assembled on solid or liquid phase using β-alanine and γ-aminobutyric acid, followed by simultaneous N- and O- deprotection and double bond reduction using catalytic hydrogenation.

TL;DR: The structure and biological significance of naturally occurring and synthetic polyamine analogues and conjugates are presented and the available methodologies for their synthesis are described in this paper, which involve either the selective functionalization of the amino functions, using suitable protecting groups or acylating agents, or fragment synthesis protocols.

TL;DR: Acylation of a variety of amines with succinimidyl N-trityl-β-alanyl-γ-aminobutyrate and N- TRITYl-γ -aminobutyryl- β-alaninate produced N-monoalkylated spermidine fragments and analogues of the spermine alkaloid kukoamine A.

TL;DR: In this article, the authors focused on the stabilization of cellulases by cross-linking or by the addition of specific crown ether based compounds to improve glucose production and showed that enzymatic treatment of waste paper is of particular interest, since it may be an alternative way to carry out municipal wastes treatment and concomitant glucose production.