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Aglaia Athanassiadou
Researcher at University of Patras
Publications - 46
Citations - 8794
Aglaia Athanassiadou is an academic researcher from University of Patras. The author has contributed to research in topics: Gene & Transgene. The author has an hindex of 23, co-authored 44 publications receiving 8121 citations. Previous affiliations of Aglaia Athanassiadou include Guy's Hospital.
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Journal ArticleDOI
Mutation in the α-synuclein gene identified in families with Parkinson's disease
Mihael H. Polymeropoulos,Christian Lavedan,Elisabeth Leroy,Susan E. Ide,Anindya Dehejia,Amalia Dutra,Brian L. Pike,Holly Root,Jeffrey Rubenstein,Rebecca Boyer,Edward S. Stenroos,Settara C. Chandrasekharappa,Aglaia Athanassiadou,Theodore Papapetropoulos,William G. Johnson,Alice Lazzarini,Roger C. Duvoisin,Giuseppe Di Iorio,Lawrence I. Golbe,Robert L. Nussbaum +19 more
TL;DR: A mutation was identified in the α-synuclein gene, which codes for a presynaptic protein thought to be involved in neuronal plasticity, in the Italian kindred and in three unrelated families of Greek origin with autosomal dominant inheritance for the PD phenotype.
Journal ArticleDOI
Genetic analysis of families with Parkinson disease that carry the Ala53Thr mutation in the gene encoding alpha-synuclein.
Aglaia Athanassiadou,Gerassimos E. Voutsinas,Lambrini Psiouri,Elisabeth Leroy,Mihael H. Polymeropoulos,Achilleas Ilias,George M. Maniatis,Thodoros Papapetropoulos +7 more
TL;DR: This work aims to demonstrate the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds.
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Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: the importance of CYP2C19*2 genotyping
Dimitrios Alexopoulos,Gerasimos Dimitropoulos,Periklis Davlouros,Ioanna Xanthopoulou,George Kassimis,Eleana F. Stavrou,George Hahalis,Aglaia Athanassiadou +7 more
TL;DR: In patients with HTPR after PCI, prasugrel is more effective compared with high clopidogrel in reducing platelet reactivity, particularly in CYP2C19*2 carriers.
Journal ArticleDOI
Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element.
TL;DR: The results provide the first evidence that S/MAR-based plasmids can function as stable episomes in primary human cells, supporting long-term transgene expression, and do not display universal behavior in all cell types.
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Genetic modification of hematopoietic stem cells with nonviral systems : past progress and future prospects
TL;DR: It is argued that episomally maintained self-replicating vectors combined with physical methods of delivery show the greatest promise among nonviral gene transfer strategies for the treatment of disorders of the hematopoietic system.