G
Georges Olive
Researcher at Paris Descartes University
Publications - 73
Citations - 2096
Georges Olive is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Pharmacokinetics & Volume of distribution. The author has an hindex of 25, co-authored 73 publications receiving 2049 citations.
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Pharmacokinetics of midazolam in children: comparative study of intranasal and intravenous administration.
TL;DR: Children randomly assigned to receive midazolam 0.2 mg·kg−1 either by the intravenous (IV) or intranasal (IN) routes showed consistent with an estimated mean bioavailability of 55%.
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The pharmacokinetics of rectal midazolam for premedication in children.
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A randomized, double‐blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children
L. Bertin,Gérard Pons,Philippe d'Athis,J.-F. Duhamel,C. Maudelonde,G. Lasfargues,M. Guillot,A Marsac,B Debregeas,Georges Olive +9 more
TL;DR: There is no argument to emphasize the utility of nonsteroidal anti‐inflammatory drugs (NSAIDs) in treating the inflammatory signs of the tympanic membrane in otitis and the efficacy of IBU was evidenced on the relief of pain, the symptom that most disturbs the child.
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Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults.
C. Cazeneuve,Gérard Pons,E. Rey,Jean-Marc Treluyer,T. Cresteil,G Thiroux,Philippe d'Athis,Georges Olive +7 more
TL;DR: The delay in the maturation of N-1 compared with N-3 and N-7-demethylation is in agreement with previous in vivo data, and the difference in maturational profiles of each metabolic pathway suggests that the reactions depend on different isoenzymes.
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Randomized, double-blind, multicenter, controlled trial of ibuprofen versus acetaminophen (paracetamol) and placebo for treatment of symptoms of tonsillitis and pharyngitis in children.
L. Bertin,Gérard Pons,Philippe d'Athis,G. Lasfargues,C. Maudelonde,J.-F. Duhamel,Georges Olive +6 more