G
Géraldine A. Van der Auwera
Researcher at Université catholique de Louvain
Publications - 15
Citations - 5926
Géraldine A. Van der Auwera is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Plasmid & Bacillus thuringiensis. The author has an hindex of 14, co-authored 15 publications receiving 4702 citations. Previous affiliations of Géraldine A. Van der Auwera include Broad Institute & University of Idaho.
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Journal ArticleDOI
From FastQ Data to High‐Confidence Variant Calls: The Genome Analysis Toolkit Best Practices Pipeline
Géraldine A. Van der Auwera,Mauricio O. Carneiro,Christopher Hartl,Ryan Poplin,Guillermo del Angel,Ami Levy-Moonshine,Tadeusz Jordan,Khalid Shakir,David Roazen,Joel Thibault,Eric Banks,Kiran V. Garimella,David Altshuler,Stacey Gabriel,Mark A. DePristo +14 more
TL;DR: This unit describes how to use BWA and the Genome Analysis Toolkit to map genome sequencing data to a reference and produce high‐quality variant calls that can be used in downstream analyses.
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Bacillus taxonomy in the genomic era finds phenotypes to be essential though often misleading
TL;DR: The current state of Bacillus taxonomy is discussed and two examples that highlight the ecological diversity found within identical 16S rDNA-based clusters are focused on: the identification of ecologically distinct clusters of B. simplex in Evolution Canyons and the demarcation of species in the industrially and medically important B. cereus group.
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Conjugative plasmid pAW63 brings new insights into the genesis of the Bacillus anthracis virulence plasmid pXO2 and of the Bacillus thuringiensis plasmid pBT9727.
TL;DR: The complete sequence determination of pAW63 has led to a functional map of the plasmid yielding insights into its conjugative apparatus, which includes T4SS-like components, as well as its resemblance to other large plasmids of Gram-positive bacteria.
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Broad-Host-Range Plasmids from Agricultural Soils Have IncP-1 Backbones with Diverse Accessory Genes
Diya Sen,Géraldine A. Van der Auwera,Linda M. Rogers,Christopher M. Thomas,Celeste J. Brown,Eva M. Top +5 more
TL;DR: The goal of this study was to analyze and compare the genomes of 12 broad-host-range plasmids that were previously isolated from Norwegian soils by exogenous plasmid isolation and that encode mercury resistance and proposed a hypothesis for the evolution of these Tn501-bearing IncP-1β plasmIDS that predicts recent diversification followed by worldwide spread.
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Plasmid exchanges among members of the Bacillus cereus group in foodstuffs.
TL;DR: Conjugation and mobilisation of these plasmids were shown to occur at significant levels in both food products, attaining the highest transfer frequencies in milk, with an approximately ten-fold increase in conjugative transfer in this growth medium as compared to liquid LB.