G
Gérard Helft
Researcher at Pierre-and-Marie-Curie University
Publications - 145
Citations - 7048
Gérard Helft is an academic researcher from Pierre-and-Marie-Curie University. The author has contributed to research in topics: Percutaneous coronary intervention & Myocardial infarction. The author has an hindex of 32, co-authored 134 publications receiving 6481 citations. Previous affiliations of Gérard Helft include Icahn School of Medicine at Mount Sinai & Cardiovascular Institute of the South.
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Journal ArticleDOI
Coronary artery disease: pathogenesis and acute coronary syndromes.
TL;DR: This review will focus on the current theories of atherogenesis and how they impact on the understanding of acute coronary syndromes.
Journal ArticleDOI
Noninvasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging
Zahi A. Fayad,Valentin Fuster,John T. Fallon,Timothy Jayasundera,Stephen G. Worthley,Gérard Helft,J. Gilberto Aguinaldo,Juan J. Badimon,Samin K. Sharma +8 more
TL;DR: In vivo high-spatial-resolution BB-MR provides a unique new method to noninvasively image and assess the morphological features of human coronary arteries, which may allow the identification of atherosclerotic disease before it is symptomatic.
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Effects of Lipid-Lowering by Simvastatin on Human Atherosclerotic Lesions A Longitudinal Study by High-Resolution, Noninvasive Magnetic Resonance Imaging
Roberto Corti,Zahi A. Fayad,Valentin Fuster,Stephen G. Worthley,Gérard Helft,James H. Chesebro,Michele Mercuri,Juan J. Badimon +7 more
TL;DR: It is demonstrated that effective and maintained lipid-lowering therapy by simvastatin is associated with a significant regression of atherosclerotic lesions, and suggests that statins induce vascular remodeling, as manifested by reduced atheosclerotic burden without changes in the lumen.
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Lipid lowering by simvastatin induces regression of human atherosclerotic lesions: two years' follow-up by high-resolution noninvasive magnetic resonance imaging.
Roberto Corti,Valentin Fuster,Zahi A. Fayad,Stephen G. Worthley,Gérard Helft,Donald R. Smith,Jesse Weinberger,Jolanda J. Wentzel,Gabor Mizsei,Michele Mercuri,Juan J. Badimon +10 more
TL;DR: The present study demonstrates that maintained lipid-lowering therapy with simvastatin is associated with significant regression of established atherosclerotic lesions in humans and indicates that lipid- Lowering therapy isassociated with sustained vascular remodeling and emphasize the need for longer-term treatment.
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Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology.
Phillippe Gabriel Steg,Kurt Huber,Felicita Andreotti,Harald Arnesen,Dan Atar,Lina Badimon,J.-P Bassand,R. De Caterina,J. A. Eikelboom,Dietrich C. Gulba,Martial Hamon,Gérard Helft,Keith A.A. Fox,Steen Dalby Kristensen,Sunil V. Rao,F. W. A. Verheugt,Petr Widimsky,Uwe Zeymer,Jean-Philippe Collet +18 more
TL;DR: Current knowledge regarding the epidemiology of bleeding in ACS and percutaneous coronary intervention is summarized, including measurement and definitions of bleeding, with emphasis on the recent consensus Bleeding Academic Research Consortium (BARC) definitions.