J
John T. Fallon
Researcher at New York Medical College
Publications - 384
Citations - 30084
John T. Fallon is an academic researcher from New York Medical College. The author has contributed to research in topics: Tissue factor & Myocarditis. The author has an hindex of 93, co-authored 372 publications receiving 28998 citations. Previous affiliations of John T. Fallon include East Carolina University & Emory University.
Papers
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Journal Article
Myocarditis. A histopathologic definition and classification.
HT Aretz,ME Billingham,William D. Edwards,SM Factor,John T. Fallon,Jr Jj Fenoglio,E. G. J. Olsen,Frederick J. Schoen +7 more
Journal ArticleDOI
Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture.
TL;DR: Macrophage-rich areas are more frequently found in patients with unstable angina and non-Q-wave myocardial infarction, which suggests that macrophages are a marker of unstable atherosclerotic plaques and may play a significant role in the pathophysiology of acute coronary syndromes.
Journal ArticleDOI
Blood-borne tissue factor: Another view of thrombosis
Peter L.A. Giesen,Ursula Rauch,Bernd Bohrmann,Dorothee Kling,Mercè Roqué,John T. Fallon,Juan J. Badimon,Jacques Himber,Markus A. Riederer,Yale Nemerson +9 more
TL;DR: It is suggested that blood-borne TF is inherently thrombogenic and may be involved in thrombus propagation at the site of vascular injury.
Journal Article
Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture.
Prediman K. Shah,Erling Falk,Juan J. Badimon,Antonio Fernández-Ortiz,Alessandra Mailhac,G Villareal-Levy,John T. Fallon,J Regnstrom,V Fuster +8 more
TL;DR: The hypothesis that increased macrophage density and/or activation in the atherosclerotic plaque may induce collagen breakdown in the fibrous cap by secreting MMPs and possibly other proteases, thus contributing to vulnerability to plaque rupture is supported.
Journal ArticleDOI
Tissue Factor Modulates the Thrombogenicity of Human Atherosclerotic Plaques
Vincenzo Toschi,Richard L. Gallo,M. Lettino,John T. Fallon,S. D. Gertz,Antonio Fernández-Ortiz,James H. Chesebro,Lina Badimon,Yale Nemerson,Valentin Fuster,Juan J. Badimon +10 more
TL;DR: The results show that tissue factor is present in lipid-rich human atherosclerotic plaques and suggest that it is an important determinant of the thrombogenicity of human atheosclerotic lesions after spontaneous or mechanical plaque disruption.