G
Gérard S. Chetrite
Researcher at French Institute of Health and Medical Research
Publications - 10
Citations - 223
Gérard S. Chetrite is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Adipose tissue & Adipocyte. The author has an hindex of 6, co-authored 10 publications receiving 198 citations. Previous affiliations of Gérard S. Chetrite include University of Paris-Sud.
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Journal ArticleDOI
Antiadipogenic Effects of the Mineralocorticoid Receptor Antagonist Drospirenone: Potential Implications for the Treatment of Metabolic Syndrome
Massimiliano Caprio,Antonella Antelmi,Gérard S. Chetrite,Gérard S. Chetrite,A. Muscat,A. Muscat,Caterina Mammi,Vincenzo Marzolla,Andrea Fabbri,Maria-Christina Zennaro,Maria-Christina Zennaro,Bruno Fève,Bruno Fève +12 more
TL;DR: Drospirenone exerts a potent antiadipogenic effect that is related to an alteration of the transcriptional control of adipogenesis via an antagonistic effect on the MR, and has promise as a novel therapeutic option for the control of excessive adipose tissue deposition and its related metabolic complications.
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The formation and transformation of hormones in maternal, placental and fetal compartments: biological implications
TL;DR: It is hypothesize that the fetal and placental factors controlling hormonal levels in the fetal compartment can be of capital importance in the normal development of extra-uterine life.
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Antidepressant phenelzine alters differentiation of cultured human and mouse preadipocytes.
Françoise Chiche,Morwenna Le Guillou,Gérard S. Chetrite,Françoise Lasnier,Isabelle Dugail,Christian Carpéné,Marthe Moldes,Bruno Fève +7 more
TL;DR: Findings demonstrate that an antidepressant directly and potently inhibits adipocyte lipid storage and differentiation, which could contribute to psychotropic drug side effects on energy homeostasis.
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A New Pyrroline Compound Selective for I1-Imidazoline Receptors Improves Metabolic Syndrome in Rats
Lyne Fellmann,Véronique Regnault,Hugues Greney,Vincent Gasparik,A. Muscat,Jean-Pierre Max,Luc Gigou,Valérie Oréa,Gérard S. Chetrite,Anne Pizard,Nathalie Niederhoffer,Claude Julien,Patrick Lacolley,Bruno Fève,Pascal Bousquet +14 more
TL;DR: Investigation of how targeting both the sympathetic nervous system and the adipose tissue with a drug selective for nonadrenergic I1-imidazoline receptors (I1Rs) may represent a new concept in MetS pharmacotherapy found the pyrroline derivative has beneficial effects on all the MetS abnormalities.
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Carbamazepine directly inhibits adipocyte differentiation through activation of the ERK 1/2 pathway
TL;DR: This work tested the hypothesis that CBZ could have a direct effect on adipocyte development and metabolism and found it to be plausible.