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Maria-Christina Zennaro

Researcher at French Institute of Health and Medical Research

Publications -  120
Citations -  5451

Maria-Christina Zennaro is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Aldosterone & Mineralocorticoid receptor. The author has an hindex of 38, co-authored 94 publications receiving 4867 citations. Previous affiliations of Maria-Christina Zennaro include Collège de France & Paris Descartes University.

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Journal ArticleDOI

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.

Felix Beuschlein, +35 more
- 01 Apr 2013 - 
TL;DR: Dominant somatic alterations in two members of the ATPase gene family result in autonomous aldosterone secretion in primary adrenal adenoma cells.
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Pivotal role of the mineralocorticoid receptor in corticosteroid-induced adipogenesis

Massimiliano Caprio, +5 more
- 01 Jul 2007 - 
TL;DR: Results demonstrate that MR represents an important proadipogenic transcription factor that may mediate both aldosterone and glucocorticoid effects on adipose tissue development, and may be of pathophysiological relevance to the development of obesity and the metabolic syndrome.
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Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma

Fabio L. Fernandes-Rosa, +21 more
- 01 Aug 2014 - 
TL;DR: Investigation of the prevalence of somatic mutations in aldosterone-producing adenomas in unselected patients with APA found that young women with APAs are more likely to be KCNJ5 mutation carriers; identification of specific characteristics or surrogate biomarkers of mutation status may lead to targeted treatment options.
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Prevalence, Clinical, and Molecular Correlates of KCNJ5 Mutations in Primary Aldosteronism

Sheerazed Boulkroun, +32 more
- 01 Mar 2012 - 
TL;DR: Young age and higher aldosterone levels at diagnosis suggest that KCNJ5 mutations may be associated with a more florid phenotype of primary aldosteronism, and germline mutations are not similarly causative for bilateral adrenal hyperplasia.
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A Common Polymorphism in the Mineralocorticoid Receptor Modulates Stress Responsiveness

Roel H. DeRijk, +9 more
- 01 Dec 2006 - 
TL;DR: The findings reveal that cortisol and heart rate responses to a psychosocial stressor are enhanced in carriers of the MR180V variant.