G
Giacomo Stanzani
Researcher at University College London
Publications - 15
Citations - 305
Giacomo Stanzani is an academic researcher from University College London. The author has contributed to research in topics: Thrombotic microangiopathy & Sepsis. The author has an hindex of 7, co-authored 13 publications receiving 203 citations. Previous affiliations of Giacomo Stanzani include Royal Veterinary College.
Papers
More filters
Journal ArticleDOI
The role of mitochondria in sepsis-induced cardiomyopathy.
TL;DR: The current understanding of the pathophysiology underlying myocardial dysfunction in sepsis is described, with a focus on disrupted mitochondrial processes, which may represent an adaptive response to prolonged stress that limits cell death, improving the potential for recovery.
Journal ArticleDOI
Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study.
Karla C. L. Lee,Luisa A. Baker,Giacomo Stanzani,H I K Alibhai,Yu-Mei Chang,Carolina Palacios,P Leckie,Paola Giordano,Simon L. Priestnall,Daniel J. Antoine,Rosalind E. Jenkins,Christopher E. Goldring,B. Kevin Park,Fausto Andreola,Banwari Agarwal,Rajeshwar P. Mookerjee,Nathan Davies,Rajiv Jalan +17 more
TL;DR: The survival benefit and lack of adverse effects would support clinical trials of University College London-Liver Dialysis Device in acute liver failure patients.
Journal ArticleDOI
Cutaneous and renal glomerular vasculopathy as a cause of acute kidney injury in dogs in the UK
Laura Holm,I. Hawkins,C. A. Robin,Richard Newton,Rosanne E. Jepson,Giacomo Stanzani,L. A. McMahon,Patricia A. Pesavento,T. Carr,Tristan A Cogan,C. G. Couto,Rachel E. Cianciolo,David Walker +12 more
TL;DR: This is the first report of a series of non-greyhound dogs with CRGV and AKI in the UK, a disease of unknown aetiology carrying a poor prognosis when azotaemia develops.
Journal ArticleDOI
Evaluation of the dynamic predictors of fluid responsiveness in dogs receiving goal-directed fluid therapy
TL;DR: PPV is a useful clinical tool to detect occult hypovolaemia and predict cardiovascular response to fluid challenge and is recommended as a part of GDFT in dogs undergoing abdominal procedures.
Journal ArticleDOI
A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survival
Karla C. L. Lee,Carolina Palacios Jimenez,H I K Alibhai,Yu-Mei Chang,P Leckie,Luisa A. Baker,Giacomo Stanzani,Simon L. Priestnall,Rajeshwar P. Mookerjee,Rajiv Jalan,Nathan Davies +10 more
TL;DR: A clinically relevant, translational large animal model of acute liver failure is required for testing of novel therapies to prolong survival in acute Liver failure, to permit spontaneous liver recovery or to act as a bridge to transplantation.