G
Giancarlo Morelli
Researcher at University of Naples Federico II
Publications - 159
Citations - 4870
Giancarlo Morelli is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Peptide & Drug delivery. The author has an hindex of 33, co-authored 151 publications receiving 4006 citations.
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Journal ArticleDOI
Silver nanoparticles as potential antibacterial agents.
Gianluigi Franci,Annarita Falanga,Stefania Galdiero,Luciana Palomba,Mahendra Rai,Giancarlo Morelli,Massimiliano Galdiero +6 more
TL;DR: This review aims to summarize the emerging efforts to address current challenges and solutions in the treatment of infectious diseases, particularly the use of nanosilver antimicrobials.
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Statistical and energetic analysis of side-chain conformations in oligopeptides.
TL;DR: This study of the observed side-chain conformations has led to a refinement of one of the energy parameters used in empirical conformational energy computations.
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Supramolecular aggregates containing lipophilic Gd(III) complexes as contrast agents in MRI
TL;DR: Micelles and liposomes, obtained by the aggregation of lipophilic gadolinium complexes are described, with the aim to correlate their structural and relaxometric properties.
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A new nerve growth factor-mimetic peptide active on neuropathic pain in rats.
Anna Maria Colangelo,Maria Rosaria Bianco,Luigi Vitagliano,Carlo Cavaliere,Giovanni Cirillo,Luca De Gioia,Donatella Diana,Daniele Colombo,Cristina Redaelli,Laura Zaccaro,Giancarlo Morelli,Michele Papa,Paolo Sarmientos,Lilia Alberghina,Enzo Martegani +14 more
TL;DR: The peptide with the highest “in vitro” activity (L1L4) was shown to reduce neuropathic behavior and restore neuronal function in a rat model of peripheral neuropathic pain, thereby suggesting a potential therapeutic role for this NGF-mimetic peptide.
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Marine Antimicrobial Peptides: Nature Provides Templates for the Design of Novel Compounds against Pathogenic Bacteria
Annarita Falanga,Lucia Lombardi,Gianluigi Franci,Mariateresa Vitiello,Maria Rosaria Iovene,Giancarlo Morelli,Massimiliano Galdiero,Stefania Galdiero,Stefania Galdiero +8 more
TL;DR: This review is an attempt to explore marine AMPs as a rich source of molecules with antimicrobial activity, and suggests that these peptides may act as templates for the design of more potent and less toxic compounds.