Gilbert R. Upchurch

TL;DR: Several heterologous antisera directed against either human or porcine von Willebrand factor (vWF), inhibited botrocetin-induced vWF-dependent agglutination at high concentrations but were found to enhance this reaction at low concentrations, suggesting that no single mechanism can explain the action of both of these mediators.

TL;DR: In this paper , abdominal aortic aneurysmosis (AAAs) is defined as an aorta with a diameter ≥ 3 cm and risk factors for AAA include male sex, family history of AAA, smoking, Caucasian ethnicity, and age.

TL;DR: Endoluminal repair of an infrarenal saccular aortic aneurysm was undertaken with a modular endovascular stent graft in a 74-year-old man, with results that confirmed that the short open left limb of the modular graft had deployed such that the opening was completely impacted against the inferior wall of the saccULAR aneurYSm, preventing successful passage of a guide wire.

TL;DR: Elastase perfused aortic aneurysm formation is associated with early increases in MnSOD expression, which primarily occurs in the mitochondria, and strategies aimed at inhibiting oxidative stress during aneurYSm formation should focus on this specific SOD isoform.