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Gilbert R. Upchurch

Researcher at University of Florida

Publications -  525
Citations -  19791

Gilbert R. Upchurch is an academic researcher from University of Florida. The author has contributed to research in topics: Aortic aneurysm & Medicine. The author has an hindex of 68, co-authored 460 publications receiving 17175 citations. Previous affiliations of Gilbert R. Upchurch include Wayne State University & Brigham and Women's Hospital.

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Staged hybrid repair of extensive thoracoabdominal aortic aneurysms secondary to chronic aortic dissection

TL;DR: Staged hybrid TAAA repair, using a combination of proximal TEVAR with open distal repair, can be performed using established endovascular skills and technology coupled with traditional open aortic surgical techniques, with low surgical morbidity and mortality.
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Plasmin inhibition increases mmp-9 activity and decreases vein wall stiffness during venous thrombosis resolution

TL;DR: AP inhibition of the plasmin system was associated with larger thrombi but less vein wall injury, but no difference in other measures of resolution, possibly because of increased vein wall MMP-9 activity.
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Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms

TL;DR: The rodent aortic aneurysm model exhibits upregulation of MT1-MMP expression and protein with subsequent increased conversion of MMP-2 from the latent to the cleaved form.
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Socioeconomic Distressed Communities Index associated with worse limb-related outcomes after infrainguinal bypass.

TL;DR: Patients from severely distressed communities were found to have increased rates of MALEs, an association that persisted long term, and Mitigating risk associated with socioeconomic determinants of health has the potential to improve outcomes for patients with peripheral artery disease.