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Giorgio Bolis

Researcher at Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Publications -  66
Citations -  4497

Giorgio Bolis is an academic researcher from Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. The author has contributed to research in topics: Ovarian cancer & Chemotherapy. The author has an hindex of 25, co-authored 66 publications receiving 4279 citations.

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Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: results of a large European phase II study.

TL;DR: Topotecan in a daily-times-five schedule is an effective regimen as second-line treatment in ovarian cancer in patients who had failed to respond to one prior cisplatin-based chemotherapeutic regimen.
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Topotecan for the treatment of advanced epithelial ovarian cancer: an open-label phase II study in patients treated after prior chemotherapy that contained cisplatin or carboplatin and paclitaxel.

TL;DR: As a single agent, topotecan has modest activity in women with advanced epithelial ovarian carcinoma who have progressed or not responded after one or two prior regimens with platinum and paclitaxel.