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Giovanni Bellotti

Researcher at University of São Paulo

Publications -  133
Citations -  2963

Giovanni Bellotti is an academic researcher from University of São Paulo. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 25, co-authored 133 publications receiving 2883 citations. Previous affiliations of Giovanni Bellotti include Katholieke Universiteit Leuven.

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The Medicine, Angioplasty or Surgery Study (MASS): A prospective, randomized trial of medical therapy, balloon angioplasty or bypass surgery for single proximal left anterior descending artery stenoses

TL;DR: The more aggressive therapeutic approach with initial bypass surgery for patients with a single severe proximal stenosis of the left anterior descending coronary artery is associated with a lower incidence of medium-term adverse events than coronary angioplasty or medical treatment.
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Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: Light microscopy and immunohistochemical findings.

TL;DR: The striking correlation between the presence of T. cruzi antigen(s) with the severity of site of the inflammatory infiltrate supports a direct role for the parasite in the perpetuation of myocardial inflammation in Chagas' disease.
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Inhaled nitric oxide leading to pulmonary edema in stable severe heart failure.

TL;DR: The absence of pulmonary edema in these patients in the nitroprusside study reinforces the importance of selective nitric oxide effects in pulmonary circulation.
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Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.

TL;DR: The recognition of a heart-specific T. cruzi crossreactive epitope, in strong association with the presence of chronic heart lesions, suggests the involvement of crossreactivity between cardiac myosin and B13 in the pathogenesis of CCC.
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Sildenafil effects on exercise, neurohormonal activation, and erectile dysfunction in congestive heart failure: a double-blind, placebo-controlled, randomized study followed by a prospective treatment for erectile dysfunction.

TL;DR: Sildenafil was tolerated and effective for ED treatment in CHF, and improved the exercise capacity, which could theoretically decrease the myocardial oxygen consumption during sexual activity.