Giovanni Defazio

TL;DR: Detailed examination of available familial and genetic data indicates that the different forms of primary late-onset dystonia share aetiological factors, most probably genetic.

TL;DR: It is argued that abnormal spatial and temporal processing of sensory information produces incorrect signals for the preparation and execution of voluntary movement and is likely to be a consequence of the dopaminergic denervation of the basal ganglia that is the hallmark of PD.

TL;DR: In this article, a case-control study was conducted to determine whether pain is more frequent among people with Parkinson disease (PD) than among age-matched controls, using logistic regression models taking into account type of pain, time between pain and PD onset, and possible confounders.

TL;DR: From analysis of methodological information from 14 selected studies, it is concluded that all studies on the basis of treatment settings or record-linkage systems were probably flawed by incomplete ascertainment; the third population-based study provided the largest prevalence for late-onset dystonia but probably overestimated the prevalence of the disorder.

TL;DR: Data support the hypothesis that pain begins at clinical onset of PD or thereafter as a nonmotor feature of PD.