Glória Queiroz

TL;DR: An ethnopharmacological study carried out in two councils belonging to Trás-os-Montes region a small area located in the northern of Portugal, finding that medicinal plants, most of the species wild, are still in use among farmers, shepherds and other people who live far from villages and built-up areas.

TL;DR: The present results identify one adenyl compound thus released, namely ATP, and identify astrocytes as one source and the release is brought about by activation of any of the three ionotropic glutamate receptor types-N-methyl-D-aspartate, AMPA and kainate receptors.

TL;DR: The results confirm the previous observation that activation of N-methyl-D-aspartate, AMPA and kainate receptors induces release of ATP from astrocytes in culture and suggests that ATP may act as an autocrine or paracrine messenger between these glial cells.

TL;DR: In the prostatic portion of the rat vas deferens, endogenous ATP exerts a dual and opposite modulation of noradrenaline release: an inhibition through activation of P2Y receptors with a pharmacological profile similar to that of the P2 Y12 and P2y13 receptors and a facilitation through activationof P2X receptors withA pharmacological profiles similar to those of P 2X1 and P3X3, or PX2/P2X3 receptors.

TL;DR: In rat tail artery, inhibitory (A1 and P2Y) and facilitatory (A2A) purinoceptors are present and modulate noradrenaline release evoked by electrical stimulation, whereas a tonic activation of inhibitory A1 purinoCEPTors seems to be prevented by adenosine uptake.