G
Goncalo Rodrigues
Researcher at Instituto Superior Técnico
Publications - 16
Citations - 127
Goncalo Rodrigues is an academic researcher from Instituto Superior Técnico. The author has contributed to research in topics: Induced pluripotent stem cell & Phase noise. The author has an hindex of 6, co-authored 15 publications receiving 117 citations. Previous affiliations of Goncalo Rodrigues include University of Lisbon.
Papers
More filters
Journal ArticleDOI
Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient‐specific neural cells
Tiago G. Fernandes,Sofia T. Duarte,Mehrnaz Ghazvini,Cláudia Gaspar,Diana C. Santos,Ana R. Porteira,Goncalo Rodrigues,Simone Haupt,Diogo M. Rombo,Diogo M. Rombo,Judith Armstrong,Ana M. Sebastião,Ana M. Sebastião,Joost Gribnau,Angels García-Cazorla,Oliver Brüstle,Domingos Henrique,Joaquim M. S. Cabral,Maria Margarida Diogo +18 more
TL;DR: An approach is reported that reproduces neural commitment from human induced pluripotent stem cells using dual-SMAD inhibition under defined conditions in a vitronectin-based monolayer system and is expected to contribute with an optimized approach to study the neural commitment of human PSCs and to produce patient-specific neural cells that can be used to gain a better understanding of disease mechanisms.
Journal ArticleDOI
Clinical-scale purification of pluripotent stem cell derivatives for cell-based therapies.
Goncalo Rodrigues,Carlos A V Rodrigues,Tiago G. Fernandes,Maria Margarida Diogo,Joaquim M. S. Cabral +4 more
TL;DR: The working principles behind separation methods that have facilitated the safe and controlled application of hPSC‐derived cells in laboratory settings and pre‐clinical research are reviewed.
Journal ArticleDOI
Integrated platform for production and purification of human pluripotent stem cell-derived neural precursors.
Goncalo Rodrigues,Andreia F. S. Matos,Tiago G. Fernandes,Carlos A V Rodrigues,Michael Peitz,Simone Haupt,Maria Margarida Diogo,Oliver Brüstle,Joaquim M. S. Cabral +8 more
TL;DR: The integration of the MACS depletion step with the neural commitment protocol paves the way towards the establishment of a novel bioprocess for production of purified populations of hPSC-derived neural cells for different applications.
Journal ArticleDOI
Homotopy quantum field theories and the homotopy cobordism category in dimension 1 + 1
TL;DR: In this paper, the authors define the category of homotopy quantum field theories (HQFT) as TQFT for manifolds endowed with extra structure in the form of a map into some background space X.
Journal ArticleDOI
Vasoactive intestinal peptide in the hamster seminal vesicle: Distribution, binding sites and possible functions
Mário Pinho,Ana M. Sebastião,Goncalo Rodrigues,C P Barroso,Joana Ribeiro,Lucinda R. Mata,S. Gulbenkian +6 more
TL;DR: The results suggest that in the hamster seminal vesicle, vasoactive intestinal peptide is involved in the modulation of muscarinic function and in the control of secretion.