Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

An overview of the self-organizing map algorithm, on which the papers in this issue are based, is presented in this article.

The Self-Organizing Map

Doing qualitative research: a practical handbook, by David Silverman, Los Angeles, Sage, 2010, 456 pp., AU$65.00, ISBN 978-1-84860-033-1, ISBN 978-1-94960-034-8. Available in Australia and New Zeal...

Doing qualitative research: a practical handbook

本文对国际科学计量学杂志《Ｓｃｉｅｎｔｏｍｅｔｒｉｃｓ》１９７９－１９９１年的研究论文内容、栏目、作者及国别和编委及国别作了计量分析，揭示出科学计量学研究的重点、活动的中心及发展趋势，说明了学科带头人在发展科学计量学这门新兴学科中的作用。

国际刊物《Scientometrics》文献计量研究

In a very significant development for eHealth, broad adoption of Web 2.0 technologies and approaches coincides with the more recent emergence of Personal Health Application Platforms and Personally Controlled Health Records such as Google Health, Microsoft HealthVault, and Dossia. "Medicine 2.0" applications, services and tools are defined as Web-based services for health care consumers, caregivers, patients, health professionals, and biomedical researchers, that use Web 2.0 technologies and/or semantic web and virtual reality approaches to enable and facilitate specifically 1) social networking, 2) participation, 3) apomediation, 4) openness and 5) collaboration, within and between these user groups. The Journal of Medical Internet Research (JMIR) publishes a Medicine 2.0 theme issue and sponsors a conference on "How Social Networking and Web 2.0 changes Health, Health Care, Medicine and Biomedical Research", to stimulate and encourage research in these five areas.

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Medicine 2.0: Social Networking, Collaboration, Participation, Apomediation, and Openness

To investigate the impact of visualizing car uncertainty on drivers' trust during an automated driving scenario, a simulator study was conducted. A between-group design experiment with 59 Swedish drivers was carried out where a continuous representation of the uncertainty of the car's ability to autonomously drive during snow conditions was displayed to one of the groups, whereas omitted for the control group. The results show that, on average, the group of drivers who were provided with the uncertainty representation took control of the car faster when needed, while they were, at the same time, the ones who spent more time looking at other things than on the road ahead. Thus, drivers provided with the uncertainty information could, to a higher degree, perform tasks other than driving without compromising with driving safety. The analysis of trust shows that the participants who were provided with the uncertainty information trusted the automated system less than those who did not receive such information, which indicates a more proper trust calibration than in the control group.

Presenting system uncertainty in automotive UIs for supporting trust calibration in autonomous driving

This paper presents a first attempt to evaluate two previously proposed methods for statistical anomaly detection in sea traffic, namely the Gaussian Mixture Model (GMM) and the adaptive Kernel Density Estimator (KDE). A novel performance measure related to anomaly detection, together with an intermediate performance measure related to normalcy modeling, are proposed and evaluated using recorded AIS data of vessel traffic and simulated anomalous trajectories. The normalcy modeling evaluation indicates that KDE more accurately captures finer details of normal data. Yet, results from anomaly detection show no significant difference between the two techniques and the performance of both is considered suboptimal. Part of the explanation is that the methods are based on a rather artificial division of data into geographical cells. The paper therefore discusses other clustering approaches based on more informed features of data and more background knowledge regarding the structure and natural classes of the data.

/pdf/anomaly-detection-in-sea-traffic-a-comparison-of-the-59sh2smtj2.pdf

Anomaly detection in sea traffic - A comparison of the Gaussian Mixture Model and the Kernel Density Estimator

Detection of anomalous trajectories is an important problem in the surveillance domain. Various algorithms based on learning of normal trajectory patterns have been proposed for this problem. Yet, these algorithms typically suffer from one or more limitations: They are not designed for sequential analysis of incomplete trajectories or online learning based on an incrementally updated training set. Moreover, they typically involve tuning of many parameters, including ad-hoc anomaly thresholds, and may therefore suffer from overfitting and poorly-calibrated alarm rates. In this article, we propose and investigate the Sequential Hausdorff Nearest-Neighbor Conformal Anomaly Detector (SHNN-CAD) for online learning and sequential anomaly detection in trajectories. This is a parameter-light algorithm that offers a well-founded approach to the calibration of the anomaly threshold. The discords algorithm, originally proposed by Keogh et al. , is another parameter-light anomaly detection algorithm that has previously been shown to have good classification performance on a wide range of time-series datasets, including trajectory data. We implement and investigate the performance of SHNN-CAD and the discords algorithm on four different labeled trajectory datasets. The results show that SHNN-CAD achieves competitive classification performance with minimum parameter tuning during unsupervised online learning and sequential anomaly detection in trajectories.

Online Learning and Sequential Anomaly Detection in Trajectories

In medicinal chemistry programs it is key to design and make compounds that are efficacious and safe. This is a long, complex, and difficult multiparameter optimization process, often including several properties with orthogonal trends. New methods for the automated design of compounds against profiles of multiple properties are thus of great value. Here we present a fragment-based reinforcement learning approach based on an actor-critic model, for the generation of novel molecules with optimal properties. The actor and the critic are both modeled with bidirectional long short-term memory (LSTM) networks. The AI method learns how to generate new compounds with desired properties by starting from an initial set of lead molecules and then improving these by replacing some of their fragments. A balanced binary tree based on the similarity of fragments is used in the generative process to bias the output toward structurally similar molecules. The method is demonstrated by a case study showing that 93% of the generated molecules are chemically valid and more than a third satisfy the targeted objectives, while there were none in the initial set.

Deep Reinforcement Learning for Multiparameter Optimization in de novo Drug Design.

Surveillance of large land, air or sea areas with a multitude of sensor and sensor types typically generates huge amounts of data. Human operators trying to establish individual or collective maritime situation awareness are often overloaded by this information. In order to help them cope with this information overload, we have developed a combined methodology of data visualization, interaction and mining techniques that allows filtering out anomalous vessels, by building a model over normal behavior from which the user can detect deviations. The methodology includes a set of interactive visual representations that support the insertion of the userpsilas knowledge and experience in the creation, validation and continuous update of the normal model. Additionally, this paper presents a software prototype that implements the suggested methodology.

/pdf/improving-maritime-anomaly-detection-and-situation-awareness-5a9z4vpev4.pdf

Göran Falkman

Papers

Presenting system uncertainty in automotive UIs for supporting trust calibration in autonomous driving

Anomaly detection in sea traffic - A comparison of the Gaussian Mixture Model and the Kernel Density Estimator

Online Learning and Sequential Anomaly Detection in Trajectories

Deep Reinforcement Learning for Multiparameter Optimization in de novo Drug Design.

Improving maritime anomaly detection and situation awareness through interactive visualization