G
Gregory L. Shipley
Researcher at University of Texas Health Science Center at Houston
Publications - 43
Citations - 15751
Gregory L. Shipley is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Endometrium & Estrogen. The author has an hindex of 28, co-authored 41 publications receiving 13668 citations. Previous affiliations of Gregory L. Shipley include University of Texas MD Anderson Cancer Center & University of Texas at Austin.
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Journal ArticleDOI
Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor α in the adult rodent heart
Martin E. Young,Sarita U. Patil,Jun Ying,Christophe Depre,Harleen Singh Ahuja,Gregory L. Shipley,Stanislaw M. Stepkowski,Peter J.A. Davies,Heinrich Taegtmeyer +8 more
TL;DR: Results suggest that in the adult rodent heart, UCP‐3 expression is regu¬lated by PPARα, in contrast, cardiac U CP‐2 expression is regulated in part by a fatty acid‐dependent, PPAR α‐independent mechanism.
Journal ArticleDOI
Localization of pendrin in mouse kidney.
Susan M. Wall,Kathryn A. Hassell,Ines E. Royaux,Eric D. Green,Judy Y. Chang,Gregory L. Shipley,Jill W. Verlander +6 more
TL;DR: Pendrin is expressed in the mouse distal convoluted tubule, CCD, and CNT along the apical plasma membrane of non-A-non-B intercalated cells and in subapical cytoplasmic vesicles of type B intercalate cells.
Journal ArticleDOI
Downregulation of Metabolic Gene Expression in Failing Human Heart before and after Mechanical Unloading
Peter Razeghi,Martin E. Young,Jun Ying,Christophe Depre,Ivan P. Uray,June Kolesar,Gregory L. Shipley,Christine S. Moravec,Peter J.A. Davies,O.H. Frazier,Heinrich Taegtmeyer +10 more
TL;DR: Although LVAD treatment improved clinical markers of heart failure, only UCP3 expression reversed to non-failing transcript levels following mechanical unloading, which may be an important mechanism for reducing the formation of oxygen-derived free radicals.
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Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity.
Peter J.A. Davies,Stacey A. Berry,Gregory L. Shipley,Robert H. Eckel,Nathalie Hennuyer,Diane L. Crombie,Kathleen M. Ogilvie,Julia Peinado-Onsurbe,Catherine Fievet,Mark D. Leibowitz,Richard A. Heyman,Johan Auwerx +11 more
TL;DR: These studies demonstrate that RXR ligands can have dramatic effects on the post-translational processing of LPL and suggest that skeletal muscle may be an important target of rexinoid action, which is distinct from either retinoic acid receptor or peroxisome proliferator-activated receptor activation.
Journal ArticleDOI
Coordinate regulation of the production and signaling of retinoic acid by estrogen in the human endometrium
Lei Deng,Gregory L. Shipley,David S. Loose-Mitchell,George M. Stancel,Russell Broaddus,James H. Pickar,Peter J.A. Davies +6 more
TL;DR: The results suggest that estrogen coordinately up-regulates RA production and signaling in the human endometrium, and this coordinate mechanism may play a role in the antiproliferative effects that counterbalance the estrogen-induced endometrial proliferation.