P
Peter J.A. Davies
Researcher at Texas A&M University
Publications - 153
Citations - 10527
Peter J.A. Davies is an academic researcher from Texas A&M University. The author has contributed to research in topics: Tissue transglutaminase & Retinoic acid. The author has an hindex of 57, co-authored 152 publications receiving 10167 citations. Previous affiliations of Peter J.A. Davies include University of Texas at Austin & Thomas Jefferson University.
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Journal ArticleDOI
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
Ranjan Mukherjee,Peter J.A. Davies,Diane L. Crombie,Eric D. Bischoff,Rosemary Cesario,Lily Jow,Lawrence G. Hamann,Marcus F. Boehm,Carl E. Mondon,Alex M. Nadzan,James R. Paterniti,Richard A. Heyman +11 more
TL;DR: The data suggest that the RXR:PPARγ heterodimer is a single-function complex serving as a molecular target for treatment of insulin resistance, and may provide a new and effective treatment for NIDDM.
Journal ArticleDOI
Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones.
Peter J.A. Davies,Dana R. Davies,Alexander Levitzki,Alexander Levitzki,Frederick R. Maxfield,Pierre Milhaud,Mark C. Willingham,Ira Pastan +7 more
TL;DR: The present results strongly suggest that protein cross-linking may be essential for receptor-mediated endocytosis of some protein and polypeptide hormones.
Journal ArticleDOI
Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy
Christophe Depre,Gregory L. Shipley,Wenhao Chen,Qiuying Han,Torsten Doenst,Meredith L. Moore,Stanislaw M. Stepkowski,Peter J.A. Davies,Heinrich Taegtmeyer +8 more
TL;DR: In this article, the authors compared the patterns of gene expression in unloaded rat heart with those in hypertrophied rat heart and found that both conditions induced a re-expression of growth factors and proto-oncogenes, and a downregulation of the adult isoforms, but not of the 'fetal' isoforms.
Journal Article
Apoptosis: Molecular mechanisms in programmed cell death
Journal ArticleDOI
Retinoid X receptors: X-ploring their (patho)physiological functions
TL;DR: Retinoid X receptor belongs to a family of ligand-activated transcription factors that regulate many aspects of metazoan life and is placed into the evolution of nuclear receptors, structural details and ligands of the receptor are reviewed.