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Guan-Yu Chen

Researcher at National Chiao Tung University

Publications -  47
Citations -  2117

Guan-Yu Chen is an academic researcher from National Chiao Tung University. The author has contributed to research in topics: Autophagy & Graphene. The author has an hindex of 22, co-authored 42 publications receiving 1776 citations. Previous affiliations of Guan-Yu Chen include Massachusetts Institute of Technology & National Tsing Hua University.

Papers
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Journal ArticleDOI

A graphene-based platform for induced pluripotent stem cells culture and differentiation.

Guan-Yu Chen, +4 more
- 01 Jan 2012 - 
TL;DR: It is reported on that G and GO can support the mouse iPSCs culture and allow for spontaneous differentiation, and implicate the potentials of graphene-based materials as a platform for iPSC culture and diverse applications.
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Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide.

Guan-Yu Chen, +10 more
- 01 Sep 2012 - 
TL;DR: It is demonstrated that GO treatment of cells simultaneously triggers autophagy and TLR4/TLR9-regulated inflammatory responses, and the Autophagy was at least partly regulated by the TLRs pathway.
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Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation.

Chiu-Ling Chen, +6 more
- 01 Mar 2015 - 
TL;DR: The molecular mechanisms of how PTENP1 repressed the tumorigenic properties of HCC cells were unveiled and the potential of the SB-BV hybrid vector for PTENp1 lncRNA modulation and HCC therapy was demonstrated.
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Baculovirus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications.

Chi-Yuan Chen, +3 more
- 01 Nov 2011 - 
TL;DR: This article extensively reviews the recent understandings of the molecular mechanisms pertinent to baculovirus entry and cellular responses, and covers the latest advances in the vector improvements and applications, with special emphasis on antiviral therapy, cancer therapy, regenerative medicine and vaccine.
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Graphene Oxide Triggers Toll-Like Receptors/Autophagy Responses In Vitro and Inhibits Tumor Growth In Vivo

Guan-Yu Chen, +6 more
- 01 Sep 2014 - 
TL;DR: It is shown that GO itself can induce the toll‐like receptors (TLRs) responses and autophagy in cancer cells and confer antitumor effects in mice and implicate the potential of GO as an effective nanomaterial for Autophagy induction and cancer therapy.