Guangyao Lv

TL;DR: The potential of Lx2-32c as a candidate antitumor agent for the treatment of prostate cancer is demonstrated, with results equivalent to those of docetaxel.

TL;DR: A new tool compound is found which shows excellent therapeutic potential against human gastric cancer most likely through targeting TRPC6 channels.

TL;DR: The results demonstrate that nitrated substitutions at C-3 of ocotillol-type derivatives could provide an approach to expand their antibacterial spectrum, and that ocotilla-type triterpenoids may also be developed as appropriate carriers for NO donors in antibacterial agent discovery with low cytotoxicity.

TL;DR: Pseudoginsenoside F11 enhanced rather than inhibited the anti-tumor activity of cispaltin in murine melanoma and Lewis lung cancer xenograft tumor models, suggesting that administering F11 with cisplatin might alleviate the associated nephrotoxicity without compromising its therapeutic efficiency.

TL;DR: It is demonstrated that the tested AChEIs, excluding neostigmine, could attenuate APAP-induced liver injury, accompanied by reduced reactive oxygen species formation, adenosine triphosphate and cytochrome C loss, c-Jun N-terminal kinase 2 (JNK2) phosphorylation, and cytokines.