Guillermo Calero

TL;DR: The crystallization and x-ray structure determination of a p-mercaptobenzoic acid–protected gold nanoparticle, which comprises 102 gold atoms and 44 p-MBAs, is reported, which is chiral, with the two enantiomers alternating in the crystal lattice.

TL;DR: A unified view of principles that underlie the stability of particles protected by thiolate or phosphine and halide ligands is provided and is best described by a “noble-gas superatom” analogy.

TL;DR: A 3.8-amplitude structure of an RNA polymerase II-general transcription factor TFIIB complex at 4.5 angstrom resolution was obtained in this article.

TL;DR: Yeast Mediator proteins interacting with Med17(Srb4) have been expressed at a high level with the use of recombinant baculoviruses and recovered in homogeneous form as a seven subunit, 223 kDa complex, which evidently controls Mediator-RNA polymerase II and Mediation-promoter interactions.

TL;DR: The crystal structure of the essential Mediator head module is reported and architectural principles underlying the role of Mediator in the regulation of gene expression are revealed, suggesting that the head module juxtaposes transcription factor IIH and the carboxy-terminal domain of the largest subunit of Pol II, thereby facilitating phosphorylation of the carboxesy- terminal domain ofPol II.