G
Günther M. Keil
Researcher at Friedrich Loeffler Institute
Publications - 81
Citations - 3242
Günther M. Keil is an academic researcher from Friedrich Loeffler Institute. The author has contributed to research in topics: Virus & Bovine herpesvirus 1. The author has an hindex of 31, co-authored 79 publications receiving 2890 citations.
Papers
More filters
Journal ArticleDOI
Emergent Properties of Reduced-Genome Escherichia coli
György Pósfai,Guy Plunkett,Tamás Fehér,David Frisch,Günther M. Keil,Kinga Umenhoffer,Vitaliy Kolisnychenko,Buffy Stahl,Shamik S. Sharma,Monika de Arruda,Valerie Burland,Sarah W. Harcum,Frederick R. Blattner +12 more
TL;DR: Eradication of stress-induced transposition evidently stabilized the MDS genomes and provided some of the new properties and led to unanticipated beneficial properties: high electroporation efficiency and accurate propagation of recombinant genes and plasmids that were unstable in other strains.
Journal ArticleDOI
Course and transmission characteristics of oral low-dose infection of domestic pigs and European wild boar with a Caucasian African swine fever virus isolate.
Jana Pietschmann,Claire Guinat,Martin Beer,Valery Pronin,Kerstin Tauscher,Anja Petrov,Günther M. Keil,Sandra Blome +7 more
TL;DR: The prolonged course at the “herd level” together with the exceptionally low dose that proved to be sufficient to infect a runted wild boar could be important for disease dynamics in wild-boar populations and in backyard settings.
Journal ArticleDOI
A simple, specific, and highly sensitive blocking enzyme-linked immunosorbent assay for detection of antibodies to bovine herpesvirus 1.
J. A. Kramps,Juana Magdalena,J. Quak,K. Weerdmeester,M.J. Kaashoek,M.A. Maris-Veldhuis,Rijsewijk Franciscus Antonius,Günther M. Keil,J.T. van Oirschot +8 more
TL;DR: This blocking ELISA is superior to a commercially available indirect ELISA and to the 24-h virus neutralization test in detecting low antibody levels in serum and is able to detect specific antibodies in serum as early as 7 days postinfection.
Journal ArticleDOI
Recombination in alphaherpesviruses.
Etienne Thiry,François Meurens,Benoît Muylkens,Michael A. McVoy,Sacha Gogev,Julien Thiry,Alain Vanderplasschen,Alberto L. Epstein,Günther M. Keil,Frédéric Schynts +9 more
TL;DR: The analysis of concatemers from cells coinfected by two distinguishable alphaherpesviruses provides an efficient tool to study recombination without the bias introduced by invisible or non‐viable recombinant, and by dominance of a virus over recombinants.
Journal ArticleDOI
Virulence, immunogenicity and reactivation of bovine herpesvirus 1 mutants with a deletion in the gC, gG, gI, gE, or in both the gI and gE gene
M.J. Kaashoek,Rijsewijk Franciscus Antonius,R. C. Ruuls,Günther M. Keil,Etienne Thiry,Paul-Pierre Pastoret,J.T. van Oirschot +6 more
TL;DR: Based on residual virulence and immunogenicity, both the gG and the gE deletion mutants are candidates for incorporation in live BHV1 vaccines, however, it also depends on the kinetics of the anti-gG and anti- gE antibody response after wild-type virus infection, whether these deletion mutant are really suitable to be incorporated in a marker vaccine.