G
Guofan Xu
Researcher at University of Wisconsin-Madison
Publications - 33
Citations - 3593
Guofan Xu is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Cerebral blood flow & White matter. The author has an hindex of 21, co-authored 33 publications receiving 3128 citations. Previous affiliations of Guofan Xu include University of Wisconsin Hospital and Clinics.
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A generalized form of context-dependent psychophysiological interactions (gPPI): A comparison to standard approaches
TL;DR: The generalized form of context-dependent PPI approach has increased flexibility of statistical modeling, and potentially improves model fit, specificity to true negative findings, and sensitivity to true positive findings.
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Predictive Markers for AD in a Multi-Modality Framework: An Analysis of MCI Progression in the ADNI Population
TL;DR: Whether the multi-modal disease marker (MMDM) can predict conversion from Mild Cognitive Impairment to AD is examined, and experiments reveal that this measure shows significant group differences between MCI subjects who progressed to AD, and those who remained stable for 3 years.
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Reliability and Precision of Pseudo-Continuous Arterial Spin Labeling Perfusion MRI on 3.0 T and Comparison With 15O-water PET in Elderly Subjects at Risk for Alzheimer's Disease
Guofan Xu,Howard A. Rowley,Gaohong Wu,David C. Alsop,Ajit Shankaranarayanan,Maritza Dowling,Bradley T. Christian,Terrence R. Oakes,Sterling C. Johnson +8 more
TL;DR: The data suggest that pcASL provides a reliable whole brain CBF measurement in young and elderly adults whose results converge with those obtained with the traditional 15O‐water PET perfusion imaging method.
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Spatially augmented LPboosting for AD classification with evaluations on the ADNI dataset.
TL;DR: A new framework for AD classification is proposed which makes use of the Linear Program (LP) boosting with novel additional regularization based on spatial "smoothness" in 3D image coordinate spaces and incorporates this emphasis on spatial smoothness directly into the learning step.
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Insulin Resistance, Brain Atrophy, and Cognitive Performance in Late Middle–Aged Adults
Auriel A. Willette,Guofan Xu,Sterling C. Johnson,Alex C. Birdsill,Erin M. Jonaitis,Mark A. Sager,Bruce P. Hermann,Asenath La Rue,Sanjay Asthana,Barbara B. Bendlin +9 more
TL;DR: It is suggested that insulin resistance in an asymptomatic, late middle–aged cohort is associated with progressive atrophy in regions affected by early Alzheimer disease and the ability to encode episodic information by negatively influencing gray matter volume in medial temporal lobe.