Showing papers by "Guolan Dou published in 2007"
TL;DR: A facile synthetic method using low-valent titanium reagent (TiCl 4 /Zn system) to promote the novel reductive cyclization of 2-nitrobenzamides and triphosgene is described.
48 citations
TL;DR: In this article, a mild, efficient and novel synthesis of 2-aryl-2H-indazoles via cyclization of 2nitrobenzylamines promoted by SnCl 2 ·2H 2 O has been described.
Abstract: A mild, efficient, and novel synthesis of 2-aryl-2H-indazoles via cyclization of 2-nitrobenzylamines promoted by SnCl 2 ·2H 2 O has been described. This method applies to a wide scope of substrates containing electron-donating and electron-withdrawing substituents.
39 citations
TL;DR: In this paper, a short and efficient synthesis of substituted pyrroles was accomplished in good yields via the novel coupling cyclization reaction of 1,3-diketones with imines promoted by low-valent titanium reagent.
Abstract: A short and efficient synthesis of substituted pyrroles was accomplished in good yields via the novel coupling cyclization reaction of 1,3-diketones with imines promoted by low-valent titanium reagent. High regioselectivity was achieved and the structures of two of the products were confirmed by X-ray diffraction studies.
21 citations
TL;DR: In this article, the intermolecular reductive cyclodimerization reactions of cyclic α,β-unsaturated ketones such as 2-benzylideneindan-1-ones, 2-Benzylidsidene-1 -tetralones, 3-benZylideni-chroman-4-ones induced by a low-valent titanium reagent were studied and new spiro compounds were prepared in good yields under neutral and mild conditions.
Abstract: The intermolecular reductive cyclodimerization reactions of cyclic α,β-unsaturated ketones such as 2-benzylideneindan-1-ones, 2-benzylidene-1 -tetralones, 3-benzylidenechroman-4-ones, and 3-benzylidenethiochroman-4-ones induced by a low-valent titanium reagent were studied. Some new spiro compounds were prepared in good yields under neutral and mild conditions. High stereoselectivity was achieved and the stereochemistry of the products was confirmed by X-ray diffraction analysis.
4 citations
TL;DR: In this paper, a short and facile synthesis of a series of 3-aryl-3,4-dihydroquinazolin-2(lift-ones) was accomplished in good yields via the novel reductive cyclisation of 2-nitrobenzylamines with bis(trichloromethyl)carbonate (triphosgene) promoted by TiCl 4 /Sm system.
Abstract: A short and facile synthesis of a series of 3-aryl-3,4-dihydroquinazolin-2(lift-ones was accomplished in good yields via the novel reductive cyclisation of 2-nitrobenzylamines with bis(trichloromethyl)carbonate (triphosgene) promoted by TiCl 4 /Sm system. The structures of the products were characterised by IR, 1 H NMR and elemental analysis and the structure of 3a was confirmed by X-ray diffraction analysis.
3 citations
TL;DR: In this article, the intermolecular reductive cyclodimerization reactions of cyclic α,β-unsaturated ketones such as 2-benzylideneindan-1-ones, 2-Benzylidsidene-1 -tetralones, 3-benZylideni-chroman-4-ones induced by a low-valent titanium reagent were studied and new spiro compounds were prepared in good yields under neutral and mild conditions.
Abstract: The intermolecular reductive cyclodimerization reactions of cyclic α,β-unsaturated ketones such as 2-benzylideneindan-1-ones, 2-benzylidene-1 -tetralones, 3-benzylidenechroman-4-ones, and 3-benzylidenethiochroman-4-ones induced by a low-valent titanium reagent were studied. Some new spiro compounds were prepared in good yields under neutral and mild conditions. High stereoselectivity was achieved and the stereochemistry of the products was confirmed by X-ray diffraction analysis.