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Guruprasad Kalthur

Researcher at Manipal University

Publications -  117
Citations -  2171

Guruprasad Kalthur is an academic researcher from Manipal University. The author has contributed to research in topics: Sperm & Medicine. The author has an hindex of 22, co-authored 98 publications receiving 1508 citations. Previous affiliations of Guruprasad Kalthur include National University of Singapore & Kasturba Medical College, Manipal.

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Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage.

TL;DR: The optimized transfersomes were found to increase the cell viability and reduce the lipid peroxidation, intracellular ROS and expression of MMPs in HaCaT cells, which underline the potential application of the developed transfersomes in sunscreen cream/lotions for improvement of UV radiation-protection along with deriving antioxidant and anti-aging effects.
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Poor sperm quality and advancing age are associated with increased sperm DNA damage in infertile men.

TL;DR: Age‐related increase in sperm DNA damage and association of the same with varicocele and alcohol consumption are demonstrated, and poor sperm characteristics in the ejaculate are associated with increased sperm DNADamage.
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Vitamin E Supplementation in Semen-Freezing Medium Improves the Motility and Protects Sperm from Freeze-Thaw–Induced DNA Damage

TL;DR: Results of this study indicate that supplementation of vitamin E (5 mM) significantly improves the post-thaw motility and DNA integrity in normozoospermic and asthenozoos permic semen samples.
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Effect of cryopreservation on sperm DNA integrity in patients with teratospermia

TL;DR: The susceptibility of morphologically abnormal sperm to DNA damage/chromatin modification during the freeze-thaw process is significantly higher than that of sperm with normal morphology.