G
Gustavo Rafael Mazzaron Barcelos
Researcher at Federal University of São Paulo
Publications - 46
Citations - 1166
Gustavo Rafael Mazzaron Barcelos is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Genotoxicity & DNA damage. The author has an hindex of 19, co-authored 44 publications receiving 995 citations. Previous affiliations of Gustavo Rafael Mazzaron Barcelos include Universidade Estadual de Londrina & University of São Paulo.
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Journal ArticleDOI
Low levels of methylmercury induce DNA damage in rats: protective effects of selenium.
Denise Grotto,Gustavo Rafael Mazzaron Barcelos,Juliana Valentini,Juliana Valentini,Lusânia Maria Greggi Antunes,José Pedro Friedmann Angeli,Solange Cristina Garcia,Fernando Barbosa +7 more
TL;DR: The findings demonstrated the oxidative and genotoxic properties of MeHg, even at low doses, and co-administration reestablished GSH-Px activity and reduced DNA damage.
Journal ArticleDOI
Low level and sub-chronic exposure to methylmercury induces hypertension in rats: nitric oxide depletion and oxidative damage as possible mechanisms.
Denise Grotto,Michele M. Castro,Gustavo Rafael Mazzaron Barcelos,Solange Cristina Garcia,Fernando Barbosa +4 more
TL;DR: Long-term exposure to a low dose of MeHg increases the systolic pressure and is associated, at least in part, with increased production of ROS as judged by increasedProduction of malondialdehyde and depressed NO availability.
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Protective properties of quercetin against DNA damage and oxidative stress induced by methylmercury in rats
Gustavo Rafael Mazzaron Barcelos,Denise Grotto,Juliana Mara Serpeloni,José Pedro Friedmann Angeli,Bruno Alves Rocha,Vanessa Cristina de Oliveira Souza,Juliana Vicentini,Tatiana Emanuelli,Jairo Kenupp Bastos,Lusânia Maria Greggi Antunes,Siegfried Knasmüller,Fernando Barbosa +11 more
TL;DR: Results indicate that consumption of QC-rich foods may protect Hg-exposed humans against the adverse health effects of the metal.
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Propolis-induced genotoxicity and antigenotoxicity in Chinese hamster ovary cells.
Denise Crispim Tavares,Gustavo Rafael Mazzaron Barcelos,Lívia Ferreira Silva,Conception Cortez Chacon Tonin,Jairo Kenupp Bastos +4 more
TL;DR: The present results indicate that propolis shows the characteristic of a "Janus" compound, i.e., propolis is genotoxic at higher concentrations, while at lower concentrations it display a chemopreventive effect on doxorubicin-induced mutagenicity.
Journal ArticleDOI
Polymorphisms in glutathione-related genes modify mercury concentrations and antioxidant status in subjects environmentally exposed to methylmercury.
Gustavo Rafael Mazzaron Barcelos,Denise Grotto,Kátia Cristina de Marco,Juliana Valentini,André van Helvoort Lengert,Andréia Ávila Soares de Oliveira,Solange Cristina Garcia,Gilberto U.L. Braga,Karin Engström,Ilce Mara de Syllos Cólus,Karin Broberg,Fernando Barbosa +11 more
TL;DR: The data indicate that some GSH-related polymorphisms, such as GSTM1 and GCLM may modify MeHg metabolism and Hg-related antioxidant effects.