D
Denise Grotto
Researcher at University of São Paulo
Publications - 94
Citations - 2944
Denise Grotto is an academic researcher from University of São Paulo. The author has contributed to research in topics: Oxidative stress & Chemistry. The author has an hindex of 26, co-authored 83 publications receiving 2391 citations. Previous affiliations of Denise Grotto include Universidade Federal de Santa Maria.
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Journal ArticleDOI
Importance of the lipid peroxidation biomarkers and methodological aspects FOR malondialdehyde quantification
Denise Grotto,Lucas Santa Maria,Juliana Valentini,Clóvis Paniz,Gabriela Cristina Schmitt,Solange Cristina Garcia,Valdeci Juarez Pomblum,João Rocha,Marcelo Farina +8 more
TL;DR: Significant aspects about MDA determination, its importance in pathologies and biological samples treatment, and the selective HPLC-based assays provide a more reliable lipid peroxidation measure are described.
Journal ArticleDOI
Bacterial nanocellulose production and application: a 10-year overview
Angela Faustino Jozala,Leticia Celia de Lencastre-Novaes,André Moreni Lopes,Valéria de Carvalho Santos-Ebinuma,Priscila Gava Mazzola,Adalberto Pessoa-Jr,Denise Grotto,Marli Gerenutti,Marco Vinícius Chaud +8 more
TL;DR: Different aspects of BNC production, including types of fermentation processes and culture media, are addressed, with the aim of demonstrating the importance of these parameters and improving B NC production and permitting application in the biotechnological, medical, pharmaceutical, and food industries.
Journal ArticleDOI
Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography-visible detection.
Denise Grotto,L.D. Santa Maria,Silvana Peterini Boeira,Juliana Valentini,Mariele Feiffer Charão,Angela M. Moro,Paulo C. do Nascimento,Valdeci Juarez Pomblum,Solange Cristina Garcia +8 more
TL;DR: This technique presents advantages such as the complete release of protein bound MDA with the alkaline hydrolysis step, the removal of interferents with n-butanol extraction, mobile phase without phosphate buffer and rapid analytical processes and run times.
Journal ArticleDOI
Mercury exposure and oxidative stress in communities of the Brazilian Amazon.
Denise Grotto,Juliana Valentini,Myriam Fillion,Carlos José Souza Passos,Solange Cristina Garcia,Donna Mergler,Fernando Barbosa +6 more
TL;DR: Assessment of possible associations between biomarkers of mercury (Hg) exposure and oxidative stress in fish-eating Amazonian communities clearly demonstrated an association between Hg exposure and antioxidant stress.
Journal ArticleDOI
Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates.
Robson Luiz Puntel,Daniel Henrique Roos,Denise Grotto,Solange Cristina Garcia,Cristina W. Nogueira,João Rocha +5 more
TL;DR: It is suggested that antioxidant properties of citrate, malate and oxaloacetate were due to their ability to cancel iron redox activity by forming inactive complexes, whereas alpha-ketoglutarate and malonate pro-oxidant activity can be due to formation of active complexes with iron.