G
Guy A. Cabral
Researcher at Virginia Commonwealth University
Publications - 93
Citations - 9245
Guy A. Cabral is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Cannabinoid & Cannabinoid receptor. The author has an hindex of 37, co-authored 93 publications receiving 8554 citations. Previous affiliations of Guy A. Cabral include VCU Medical Center.
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Journal ArticleDOI
International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors
Allyn C. Howlett,Francis Barth,Tom I. Bonner,Guy A. Cabral,Pierre Casellas,William A. Devane,Christian C. Felder,Miles Herkenham,Ken Mackie,Billy R. Martin,Raphael Mechoulam,Roger G. Pertwee +11 more
TL;DR: It is considered premature to rename cannabinoid receptors after an endogenous agonist as is recommended by the International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification, because pharmacological evidence for the existence of additional types of cannabinoid receptor is emerging and other kinds of supporting evidence are still lacking.
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Acanthamoeba spp. as agents of disease in humans.
TL;DR: Since an increase in the number of cases of Acanthamoeba infections has occurred worldwide, these protozoa have become increasingly important as agents of human disease.
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Endocannabinoid signaling at the periphery: 50 years after THC
Mauro Maccarrone,Itai Bab,Tamás Bíró,Guy A. Cabral,Sudhansu K. Dey,Vincenzo Di Marzo,Justin C. Konje,George Kunos,Raphael Mechoulam,Pal Pacher,Keith A. Sharkey,Andreas Zimmer +11 more
TL;DR: The state of the art of critical eCB functions in peripheral organs is reviewed to establish consensus views on the relevance of the peripheral ECS for human health and disease pathogenesis, as well as highlighting emerging challenges and therapeutic hopes.
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Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation.
TL;DR: Results indicate that levels of the CB2 in cells of macrophage lineage undergo major modulatory changes in relation to cell activation, and since inflammatory and primed macrophages express the highest levels of CB2, the functional activities of Macrophages when in these respective states of activation may be the most sensitive to the action of cannabinoids.
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Emerging role of the cannabinoid receptor CB2 in immune regulation: therapeutic prospects for neuroinflammation.
TL;DR: The studies suggest that the CB2 may serve as a selective molecular target for therapeutic manipulation of untoward immune responses, including those associated with a variety of neuropathies that exhibit a hyperinflammatory component.