H
H. S. Conjeevaram
Researcher at National Institutes of Health
Publications - 11
Citations - 1092
H. S. Conjeevaram is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Liver biopsy & Interferon alfa. The author has an hindex of 8, co-authored 11 publications receiving 1072 citations. Previous affiliations of H. S. Conjeevaram include University of Virginia.
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Journal ArticleDOI
Hepatic failure and lactic acidosis due to fialuridine (fiau), an investigational nucleoside analogue for chronic hepatitis b
Robin Mckenzie,Michael W. Fried,Richard Sallie,H. S. Conjeevaram,Adrian M. Di Bisceglie,Yoon Park,Barbara Savarese,David E. Kleiner,Maria Tsokos,Carlos Luciano,Timothy L. Pruett,Jennifer L. Stotka,Stephen E. Straus,Jay H. Hoofnagle +13 more
TL;DR: In patients with chronic hepatitis B, treatment with fialuridine induced a severe toxic reaction characterized by hepatic failure, lactic acidosis, pancreatitis, neuropathy, and myopathy, probably caused by widespread mitochondrial damage and may occur infrequently with other nucleoside analogues.
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Ribavirin as therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial
A. M. Di Bisceglie,H. S. Conjeevaram,Michael W. Fried,Richard Sallie,Yoon Park,Cihan Yurdaydin,Mark G. Swain,David E. Kleiner,Kevin Mahaney,Jay H. Hoofnagle +9 more
TL;DR: A 6-month course of ribavirin therapy was associated with little change in liver histopathology and serum HCV RNA levels, and the effect was evaluated in a randomized, double-blind, placebo-controlled trial.
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Long-term outcome of hepatitis B virus-related glomerulonephritis after therapy with interferon alfa
H. S. Conjeevaram,Jay H. Hoofnagle,Howard A. Austin,Yoon Park,Michael W. Fried,Adrian M. Di Bisceglie +5 more
TL;DR: Interferon alfa therapy resulted in long-term remission in liver disease in 8 of 15 patients with chronic hepatitis B and glomerulonephritis, accompanied by significant improvement in markers of renal disease in the majority of patients.
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Prolonged therapy of chronic hepatitis C with ribavirin
TL;DR: In conclusion, prolonged therapy with ribavirin can result in sustained improvements in serum aminotransferases and hepatic histology in a proportion of patients with chronic hepatitis C.
Journal ArticleDOI
Management of chronic viral hepatitis in children.
TL;DR: Alpha interferon therapy hastens disease remission in a proportion of patients with chronic hepatitis B and further studies are needed to define the role of interferons in chronic HDV and HCV infection in children.